Best time to walk after ProGlide femoral artery closure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Patients undergoing transfemoral peripheral angiography or endovascular intervention who achieve hemostasis with a 6F ProGlide device will be enrolled and assigned to predefined ambulation times after the procedure. The study will monitor vascular complications, hematoma, bleeding, limb ischemia, time to ambulation, and patient comfort. Key eligibility includes common femoral artery puncture, use of 6–8F sheaths, and preoperative ABI >0.9, while those with small femoral vessels, prior puncture-site complications, significant cardiopulmonary disease, or coagulopathy are excluded. The aim is to identify an ambulation schedule that balances patient safety with shorter bed rest and greater efficiency.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Scheduled for peripheral angiography or endovascular intervention via transfemoral access.
* Femoral artery puncture site located at the common femoral artery.
* Use of 6-8F vascular sheath.
* Hemostasis achieved with 6F ProGlide closure device (defined as no active bleeding, no hematoma formation, and no ischemia of the punctured limb after closure).
* Preoperative ankle-brachial index (ABI) \> 0.9 on both sides.
* Conscious, cooperative, and with normal lower limb mobility.

Exclusion Criteria:

* Undergoing carotid artery intervention.
* Femoral artery diameter \< 5 mm, or effective lumen \< 5 mm due to plaque burden.
* History of vascular complications at the puncture site.
* Abnormal cardiopulmonary function.
* Intraoperative platelet count \< 80 × 10⁹/L, or use of thrombolytic agents.
* Cognitive impairment, uncooperative, or limited lower limb mobility.

Where it's running

• Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Hui Dong, MD — Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College
• Study coordinator: Hui Dong, MD
• Email: donghui666@sina.com
• Phone: 86-010-88322385

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.