Bedside heart ultrasound to predict successful removal of the breathing tube in ICU patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-center observational study enrolling adult ICU patients who meet standard weaning criteria. Participants will undergo transthoracic echocardiography within two hours of readiness for extubation to measure LVOT VTI, MAPSE, E/e', E/A, mitral deceleration time, and the Tei index. Patients will be monitored for 24 hours after extubation to determine weaning success, defined as maintaining spontaneous breathing without reintubation, noninvasive ventilation, or high-flow oxygen. The study aims to identify which left ventricular systolic, diastolic, and global function parameters best predict extubation outcomes to support physiologically guided weaning decisions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Currently receiving mechanical ventilation in the ICU
* Planned extubation after meeting standard weaning criteria
* Hemodynamically stable at the time of echocardiographic evaluation
* Written informed consent obtained from the patient or legally authorized representative

Exclusion Criteria:

* Surgery within the previous 24 hours
* Presence of significant valvular heart disease or known cardiomyopathy
* Inadequate acoustic window for transthoracic echocardiography
* Ongoing use of extracorporeal support (e.g., ECMO)
* Patients with Do-Not-Resuscitate (DNR) orders or expected to die within 24 hours
* Re-intubation planned prophylactically regardless of clinical status
* Pregnant patients

Where it's running

• Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital
  Istanbul, Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Engin ihsan Turan, principal investigator
• Email: enginihsan@hotmail.com
• Phone: +905382431114

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.