Basic and clinical exploration of pregnancy-induced high blood pressure
Collect Blood Pressure, Blood, Amniotic Fluid, Placenta and Other Samples From Normal Pregnant Women, Patients With Pregnancy-induced Hypertension and Those Who Have Experienced Miscarriage, and Conduct Tests on Them.
Second Affiliated Hospital of Wenzhou Medical University · NCT07464379
See if blood pressure readings and biological samples (blood, amniotic fluid, placenta) from pregnant women with high blood pressure, healthy pregnancies, and those who miscarried show biological differences.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 20 Years to 50 Years |
| Sex | Female |
| Sponsor | Second Affiliated Hospital of Wenzhou Medical University (other) |
| Locations | 1 site (Wenzhou, Zhejiang) |
| Trial ID | NCT07464379 on ClinicalTrials.gov |
What this trial studies
This observational project will collect blood pressure measurements and biological samples — including blood, amniotic fluid, and placenta — from healthy pregnant women, women with pregnancy-induced hypertension, and women who experienced miscarriage. Samples and clinical data will be analyzed in the laboratory for biochemical and molecular markers related to maternal blood pressure and pregnancy outcomes. The study does not assign treatments; participants will receive standard clinical care while providing samples and data. Enrollment and all sample collection take place at the Second Affiliated Hospital of Wenzhou Medical University in Wenzhou, Zhejiang.
Who should consider this trial
Good fit: Women who are currently pregnant (including healthy pregnancies and pregnancies with pregnancy-induced hypertension) or who have experienced miscarriage and who are willing to provide clinical information and biological samples are the intended participants.
Not a fit: Pregnant women with significant heart disease, active infections, or those unwilling to cooperate with sample collection are unlikely to be eligible or to benefit from participation.
Why it matters
Potential benefit: If successful, the work could help identify markers that predict or explain pregnancy-induced high blood pressure and support earlier or more personalized care.
How similar studies have performed: Other observational studies using blood and placental samples have identified candidate biomarkers for preeclampsia and related conditions, but no single definitive clinical test has been established yet.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Healthy pregnant women, patients with miscarriage, etc. Exclusion Criteria: * Heart disease, infections, etc. in pregnant women Uncooperative patients
Where this trial is running
Wenzhou, Zhejiang
- The Second Affiliated Hospital of Wenzhou Medical University — Wenzhou, Zhejiang, China (RECRUITING)
Study contacts
- Study coordinator: Qian Wang, PHD
- Email: wqian84@163.com
- Phone: 13587638653
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pregnancy-induced Hypertension