Basic and clinical exploration of pregnancy-induced high blood pressure
Official title: Collect Blood Pressure, Blood, Amniotic Fluid, Placenta and Other Samples From Normal Pregnant Women, Patients With Pregnancy-induced Hypertension and Those Who Have Experienced Miscarriage, and Conduct Tests on Them.
Run by Second Affiliated Hospital of Wenzhou Medical University · NCT07464379 · Data updated 2026-11-12
See if blood pressure readings and biological samples (blood, amniotic fluid, placenta) from pregnant women with high blood pressure, healthy pregnancies, and those who miscarried show biological differences.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 50 Years |
| Sex | Women only |
| Enrollment | 100 (estimated) |
| Sponsor | Second Affiliated Hospital of Wenzhou Medical University Academic / other |
| Locations | 1 site (Wenzhou, Zhejiang) |
| Status | Recruiting |
| Started | January 1, 2020 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2028 |
| Registry record updated | March 11, 2026 |
| Trial ID | NCT07464379 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women who are currently pregnant (including healthy pregnancies and pregnancies with pregnancy-induced hypertension) or who have experienced miscarriage and who are willing to provide clinical information and biological samples are the intended participants.
✕Probably not a fit
Pregnant women with significant heart disease, active infections, or those unwilling to cooperate with sample collection are unlikely to be eligible or to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational project will collect blood pressure measurements and biological samples — including blood, amniotic fluid, and placenta — from healthy pregnant women, women with pregnancy-induced hypertension, and women who experienced miscarriage. Samples and clinical data will be analyzed in the laboratory for biochemical and molecular markers related to maternal blood pressure and pregnancy outcomes. The study does not assign treatments; participants will receive standard clinical care while providing samples and data. Enrollment and all sample collection take place at the Second Affiliated Hospital of Wenzhou Medical University in Wenzhou, Zhejiang.
Why it matters
Potential benefit: If successful, the work could help identify markers that predict or explain pregnancy-induced high blood pressure and support earlier or more personalized care.
How similar studies have gone: Other observational studies using blood and placental samples have identified candidate biomarkers for preeclampsia and related conditions, but no single definitive clinical test has been established yet.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Healthy pregnant women, patients with miscarriage, etc. Exclusion Criteria: * Heart disease, infections, etc. in pregnant women Uncooperative patients
Where it's running
-
The Second Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, China Recruiting
Study contacts
- Study coordinator: Qian Wang, PHD
- Email: wqian84@163.com
- Phone: 13587638653
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.