Balance training program for people with Multiple Sclerosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of a specially adapted balance training program, HiBalance-MS, on individuals with Multiple Sclerosis (MS). The program combines motor and cognitive exercises designed to improve balance control, walking ability, and overall activity performance. Participants will be randomly assigned to receive this intervention to assess its impact on their physical and cognitive functioning. The study aims to enhance the quality of life for those affected by MS by promoting independence through improved balance and mobility.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* an MS diagnosis according to McDonald criteria;
* an overall MS-disability score from 2.0 to 5.5 according to the Expanded Disability Status Scale;
* ability to walk 100 m without aid;
* a maximum score of 24 in the Mini-BESTest (i.e., \< 25 points)
* 18 to 65 years of age

Exclusion Criteria:

* cognitive impairment as indicated by a score \<21 in the Montreal Cognitive Assessment;
* presence of other conditions that would substantially influence balance;
* an MS relapse or change of disease-modifying treatment within the past 8 weeks

Where it's running

• Karolinska Institutet
  Stockholm, Stockholm County, Sweden Recruiting

Study contacts

• Principal investigator: Sverker Johansson, Ph.D — Karolinska Institutet, org.nr 202100-2973
• Study coordinator: Compliance Office Karolinska Institutet
• Email: compliance@ki.se
• Phone: +46852480000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Balance and gait in multiple sclerosis: linking motion data to function

  Researchers will see if precise motion measurements of balance and walking relate to everyday functional tests in adults with MS.

  Recruiting at 2 sites University of Patras · Ioannina and 1 other locations · NCT07630311

• Treadmill-based virtual reality walking training for MS patients

  This study tests whether a treadmill with virtual reality and smart socks can help people with multiple sclerosis walk better and feel safer in daily life.

  Recruiting Shepherd Center, Atlanta GA · Atlanta, Georgia · NCT07927439

• Virtual Reality and Mental Practice to Improve Balance and Walking in Relapsing MS

  This study tests whether virtual reality training or mental practice can improve balance and walking in people with relapsing–remitting multiple sclerosis.

  Recruiting Cairo University · Giza, Giza Governorate · NCT07918339

• REAL-MS: A Look at Autologous Stem Cell Transplant vs High-Efficacy MS Therapies in Real-World Care

  This study tests how AHSCT compares to high-efficacy MS medicines in adults treated in routine clinical care.

  Recruiting Imperial College London · London and 2 other locations · NCT07899502

• Tolebrutinib in real-world MS care for patients treated by clinicians

  This real-world study sees how tolebrutinib is used for multiple sclerosis patients and what outcomes look like in everyday practice.

  Recruiting Sanofi · Marina, Abu Dhabi Emirate · NCT07898371

• Pilates via live video vs. prerecorded videos for people with multiple sclerosis

  This study tests whether live, coach-led Pilates sessions through video calls are more beneficial than prerecorded Pilates videos for adults with MS.

  Recruiting Yuzuncu Yil University · Van · NCT07893925

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.