Balance training program for people with Multiple Sclerosis
Motor-cognitive Performance in People With Multiple Sclerosis - Brain Activity and Effects of Balance Exercise
This study tests a new balance training program for people with Multiple Sclerosis to see if it helps them walk better and feel more independent.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 1 site (Stockholm, Stockholm County) |
| Trial ID | NCT06312046 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of a specially adapted balance training program, HiBalance-MS, on individuals with Multiple Sclerosis (MS). The program combines motor and cognitive exercises designed to improve balance control, walking ability, and overall activity performance. Participants will be randomly assigned to receive this intervention to assess its impact on their physical and cognitive functioning. The study aims to enhance the quality of life for those affected by MS by promoting independence through improved balance and mobility.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18 to 65 with a confirmed diagnosis of Multiple Sclerosis who can walk 100 meters without assistance.
Not a fit: Patients with significant cognitive impairment or other conditions that severely affect balance may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly enhance balance and cognitive performance in patients with Multiple Sclerosis, leading to improved independence and quality of life.
How similar studies have performed: Previous studies have shown success with similar balance training approaches in other neurological conditions, indicating potential for effectiveness in MS as well.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * an MS diagnosis according to McDonald criteria; * an overall MS-disability score from 2.0 to 5.5 according to the Expanded Disability Status Scale; * ability to walk 100 m without aid; * a maximum score of 24 in the Mini-BESTest (i.e., \< 25 points) * 18 to 65 years of age Exclusion Criteria: * cognitive impairment as indicated by a score \<21 in the Montreal Cognitive Assessment; * presence of other conditions that would substantially influence balance; * an MS relapse or change of disease-modifying treatment within the past 8 weeks
Where this trial is running
Stockholm, Stockholm County
- Karolinska Institutet — Stockholm, Stockholm County, Sweden (Recruiting)
Study contacts
- Principal investigator: Sverker Johansson, Ph.D — Karolinska Institutet, org.nr 202100-2973
- Study coordinator: Compliance Office Karolinska Institutet
- Email: compliance@ki.se
- Phone: +46852480000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.