Baduanjin exercise for improving fitness and bone density in hemodialysis patients

The Effect of Baduanjin on Physical Fitness and Bone Density in Maintenance Hemodialysis Patients

This study is testing whether an 18-month Baduanjin exercise program can help improve fitness and bone density in people on hemodialysis.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 50 (estimated)
• Ages: 18 Years to 75 Years
• Sex: All
• Sponsor: Affiliated Hospital of Nantong University (Academic / other)
• Locations: 1 site (Nantong, Jiangsu)
• Trial ID: NCT06346379 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the impact of an 18-month Baduanjin exercise program on physical fitness and bone density in patients undergoing maintenance hemodialysis. Fifty patients aged 18-75 will be randomly assigned to either an intervention group, which will participate in guided Baduanjin exercises three times a week, or a control group that will continue with routine treatment. The effectiveness of the intervention will be assessed through various physical fitness tests and bone mineral density measurements at baseline and at 6, 12, and 18 months. The study seeks to determine whether this traditional exercise can enhance the quality of life for hemodialysis patients.

Who should consider this trial

Good fit: Ideal candidates are hemodialysis patients aged 18-75 who have been stable on treatment for more than three months and can tolerate exercise.

Not a fit: Patients with severe comorbidities, recent infections, or those who regularly practice similar exercises may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve physical fitness and bone density in patients undergoing hemodialysis, enhancing their overall quality of life.

How similar studies have performed: While there is limited data on Baduanjin specifically, similar exercise interventions have shown positive outcomes in improving physical fitness and quality of life in chronic disease populations.

Eligibility criteria

Inclusion Criteria:

1. Age between 18 and 75 years old;
2. Having received MHD treatment in this dialysis center for more than 3 months and maintaining stable condition;
3. Having normal comprehension ability, clear verbal expression, informed consent and willingness to participate in this study.
4. Having free movement ability, and being able to tolerate Baduanjin exercise after cardiopulmonary exercise test;
5. Right-handed, with fistula in the non-dominant hand;

Exclusion Criteria:

1. Patients who usually practice traditional Chinese medicine exercises such as tai chi;
2. Patients who are recently complicated with severe infections, active malignant tumors, severe cardiopulmonary insufficiency, gastrointestinal bleeding, nervous system diseases and cannot tolerate exercise;
3. Patients with various orthopedic, neurological, and other diseases that cause muscle and joint deformities that affect grip strength measurement;
4. Patients with senile dementia, hearing impairment, comprehension abnormalities, mental disorders, unclear verbal expression or unwilling to participate in this study;
5. Patients with hemoglobin \<70g/L, carbon dioxide binding capacity \<13mmol/L, and blood potassium \>6.5mmol/L in laboratory tests and no significant improvement after treatment;
6. Patients who are participating in other clinical studies.

Where this trial is running

Nantong, Jiangsu

• Affiliated Hospital of Nantong University — Nantong, Jiangsu, China (Recruiting)

Study contacts

• Study coordinator: Li Yuan

Conditions Rehabilitation; Physical Fitness; Bone Density; Hemodialysis Complication