B-Lynch suture technique for controlling blood loss in placenta previa
B-lynch Transverse Compression Suture in the Prophylaxis and Control of Postpartum Heamorrhage in Patients With Placenta Previa: A Pilot Study
This study is testing a special stitching technique to see if it can help control heavy bleeding during cesarean sections for women with placenta previa.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 25 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Alexandria University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06359886 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the safety and effectiveness of the B-Lynch transverse compression suture in managing excessive blood loss during elective cesarean sections for women diagnosed with placenta previa. The procedure involves a specific suturing technique that aims to compress the uterus and control bleeding. The study will include women with single gestations and a history of multiple births, while excluding those with certain complications such as morbidly adherent placentas or severe health issues. The trial is conducted at Ain Shams University in Cairo.
Who should consider this trial
Good fit: Ideal candidates for this study are women with a single gestation undergoing elective cesarean sections due to diagnosed placenta previa and who have had two or more previous births.
Not a fit: Patients with morbidly adherent placentas, severe hemodynamic instability, or significant comorbidities such as cardiac or coagulopathy issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this technique could significantly reduce blood loss during cesarean sections for women with placenta previa, potentially improving maternal outcomes.
How similar studies have performed: While the B-Lynch suture technique has been used in various settings, this specific application for placenta previa is less common and may represent a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Single gestation 2. Elective CS for placenta preiva (diagnosed by transvaginal ultrasound). 3. Muliparity (para 2 or more). Exclusion Criteria: 1. Morbidly adherent placenta: accrete, increta or percreta, diagnosed by abdominal and/or transvaginal ultrasound. • Ultrasonographic features of morbidly adherent placentas: * Loss of Retro-placental sonolucent zone. * Vascular lacunae. * Myometrial thinning. * Interruption of the bladder border. 2. More than 3 previous C.S. 3. Severely haemodynamic instablility needing immediate hysterectomy. 4. Patients with the cardiac, hepatic, renal or thromboembolic disease 5. Patients with coagulopathy: * Receiving anticoagulant therapy. * With thrombocytopenia or thrombasthenia. * Known coagulation factor defect. 6. Distorted uterus as unicornuate, bicornuate, fibroid uterus and adenomyosis uteri.
Where this trial is running
Cairo
- Ain Shams University — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Ahmed S Zeerban, Msc
- Email: Ahmedzeerban@gmail.com
- Phone: +201003119968
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.