At-home dichoptic movies to improve eye alignment in children with intermittent exotropia
Improving Control of Intermittent Exotropia
We will test whether watching dichoptic movies at home for eight weeks helps children with intermittent exotropia better control their eye alignment and reduce suppression.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 4 Years to 10 Years |
| Sex | All |
| Sponsor | Retina Foundation of the Southwest Academic / other |
| Locations | 1 site (Dallas, Texas) |
| Trial ID | NCT07272005 on ClinicalTrials.gov |
What this trial studies
Children with intermittent exotropia will be randomized to watch either dichoptic or standard videos streamed at home for eight weeks. The dichoptic format presents different images to each eye to reduce interocular suppression and promote binocular cooperation. Clinical measures of eye alignment and suppression will be recorded before and after the intervention to compare outcomes between groups. Participants with prior eye muscle surgery, amblyopia, prior binocular therapy, or significant neurologic/vestibular conditions are excluded and enrollment occurs at a single center in Dallas, Texas.
Who should consider this trial
Good fit: Children diagnosed with intermittent exotropia who have not had prior eye muscle surgery or binocular treatment, do not have amblyopia or major neurologic/vestibular conditions, and are not planning surgery within six months.
Not a fit: Children with prior strabismus surgery, amblyopia, previous binocular therapy, neurological or vestibular disorders, or those planning surgery within six months are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, this could offer a non-surgical, home-based therapy that improves binocular control and may reduce the need for surgery in children with intermittent exotropia.
How similar studies have performed: Dichoptic games and movies have reduced suppression in children with amblyopia, but applying dichoptic movie therapy specifically to intermittent exotropia is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of IXT or XT at Distance \& IXT or XP at near (Basic or Pseudo Divergence Excess subtype of IXT) * No surgery planned for 6 months Exclusion Criteria: * Prior eye muscle surgery * Prior binocular treatment or vision therapy * Amblyopia * Neurological conditions, seizure disorders, vestibular abnormalities, or frequent headache * Other eye conditions (refractive error OK)
Where this trial is running
Dallas, Texas
- Retina Foundation of the Southwest — Dallas, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Eileen E Birch — Retina Foundation of the Southwest
- Study coordinator: Eileen Birch, PhD
- Email: ebirch@retinafoundation.org
- Phone: 2143633911
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.