At-home dichoptic movies to improve eye alignment in children with intermittent exotropia
Official title: Improving Control of Intermittent Exotropia
Run by Retina Foundation of the Southwest · NCT07272005 · Data updated 2026-11-12
We will test whether watching dichoptic movies at home for eight weeks helps children with intermittent exotropia better control their eye alignment and reduce suppression.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 4 Years to 10 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Retina Foundation of the Southwest Academic / other |
| Locations | 1 site (Dallas, Texas) |
| Status | Recruiting |
| Started | April 1, 2026 |
| Main results expected | February 2028 |
| Study ends | August 2028 |
| Registry record updated | April 8, 2026 |
| Trial ID | NCT07272005 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children diagnosed with intermittent exotropia who have not had prior eye muscle surgery or binocular treatment, do not have amblyopia or major neurologic/vestibular conditions, and are not planning surgery within six months.
✕Probably not a fit
Children with prior strabismus surgery, amblyopia, previous binocular therapy, neurological or vestibular disorders, or those planning surgery within six months are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Children with intermittent exotropia will be randomized to watch either dichoptic or standard videos streamed at home for eight weeks. The dichoptic format presents different images to each eye to reduce interocular suppression and promote binocular cooperation. Clinical measures of eye alignment and suppression will be recorded before and after the intervention to compare outcomes between groups. Participants with prior eye muscle surgery, amblyopia, prior binocular therapy, or significant neurologic/vestibular conditions are excluded and enrollment occurs at a single center in Dallas, Texas.
Why it matters
Potential benefit: If successful, this could offer a non-surgical, home-based therapy that improves binocular control and may reduce the need for surgery in children with intermittent exotropia.
How similar studies have gone: Dichoptic games and movies have reduced suppression in children with amblyopia, but applying dichoptic movie therapy specifically to intermittent exotropia is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of IXT or XT at Distance \& IXT or XP at near (Basic or Pseudo Divergence Excess subtype of IXT) * No surgery planned for 6 months Exclusion Criteria: * Prior eye muscle surgery * Prior binocular treatment or vision therapy * Amblyopia * Neurological conditions, seizure disorders, vestibular abnormalities, or frequent headache * Other eye conditions (refractive error OK)
Where it's running
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Retina Foundation of the Southwest
Dallas, Texas, United States Recruiting
Study contacts
- Principal investigator: Eileen E Birch — Retina Foundation of the Southwest
- Study coordinator: Eileen Birch, PhD
- Email: ebirch@retinafoundation.org
- Phone: 2143633911
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Near-eye training to improve distance eye alignment in intermittent exotropia
A home-based 12-week program tests whether training the eyes at a distance can improve control of outward eye turn in children and young adults with intermittent exotropia, and whether wearing reading glasses during training helps more.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.