Assessment of chest pain risk in patients with possible angina
ORACLE: Objective Risk Assessment in Patients With Possible Anginal Chest Pain Using Leading Technology
This study is testing if a quick online questionnaire and heart tests can help doctors figure out the risk of chest pain in people who might have angina within a day of their visit.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 30 Years and up |
| Sex | All |
| Sponsor | University of Edinburgh Academic / other |
| Locations | 1 site (Edinburgh) |
| Trial ID | NCT06325020 on ClinicalTrials.gov |
What this trial studies
The ORACLE study is an observational cohort initiative aimed at evaluating the feasibility of providing a timely risk assessment for patients experiencing suspected angina. Participants will complete a digital health questionnaire regarding their coronary artery disease risk factors and symptoms, followed by standard and personal ECGs. High sensitivity cardiac troponin levels will be measured using point-of-care assays. The goal is to stratify patients into risk categories within one working day of their referral to a rapid access chest pain clinic.
Who should consider this trial
Good fit: Ideal candidates are individuals over 30 years old who have been referred to the rapid access chest pain clinic with new onset or worsening angina.
Not a fit: Patients who have experienced acute coronary syndrome within the last three months or are unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enable faster and more accurate risk assessments for patients with chest pain, potentially leading to timely interventions.
How similar studies have performed: Other studies have shown promise in using digital tools and point-of-care testing for risk assessment in similar patient populations, indicating a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \>30 years of age * Referral to the rapid access chest pain clinic with possible new onset or worsening angina Exclusion Criteria: * Inability to give informed consent. * Previous recruitment to the study. * Acute coronary syndrome within 3 months.
Where this trial is running
Edinburgh
- NHS Lothian — Edinburgh, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Michael McDermott, MBCHB — University of Edinburgh
- Study coordinator: Michael McDermott, MBChB
- Email: michael.mcdermott@ed.ac.uk
- Phone: 07966024516
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.