Assessing whole-body metabolism in ovarian cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate changes in whole-body lipid metabolism in women diagnosed with ovarian cancer. By utilizing indirect calorimetry, the study will measure fasting and postprandial lipid metabolism before, during, and after treatment, focusing on the metabolic profile of patients undergoing cytoreductive surgery followed by chemotherapy. The research seeks to identify potential metabolic targets for treatment by understanding how ovarian cancer affects lipid metabolism. This pilot study will also evaluate the feasibility and acceptability of the study protocol.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women
* Age \>18
* Presumed ovarian cancer diagnosis (i.e. those being clinically evaluated for suspicion of ovary cancer)
* Planned treatment course for ovarian cancer involving cytoreductive surgery followed by chemotherapy
* Availability to commit to attending all study visits
* Internet access and consistent access to phone/email/text communication

Exclusion Criteria:

* Pregnancy
* Inability to provide voluntary informed consent
* Inability to consume the pre-study visit meal/snack and/or the study visit meal due to strict dietary restrictions
* Illicit substance use (e.g. cocaine, methamphetamines, heroin, street drugs) - marijuana and CBD oil and related supplements will be considered on a case-by-case basis by the principal investigators
* Circumstances and/or medical condition that would limit compliance with study requirements and protocol, as determined by the principal investigators

Where it's running

• University of Tennessee Graduate School of Medicine
  Knoxville, Tennessee, United States Recruiting

Study contacts

• Study coordinator: Jill M Maples, PhD
• Email: jmaples1@utmck.edu
• Phone: 8653059367

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.