Assessing wheeze sounds and lung function in patients with asthma and COPD
A Comparative Single Centre Study Assessing the Relationship Between Acoustic Breath Sounds as Measured by a Commercially Available Sound Recording Device Against Standard of Care (Spirometry) in the Assessment of Airflow Obstruction in Patients Who Plan to Undergo Spirometry Testing
This study is testing if a device that listens for wheeze sounds can help us understand lung function better in people with asthma and COPD.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Birmingham Academic / other |
| Locations | 1 site (Birmingham, West Midlands) |
| Trial ID | NCT06039943 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the relationship between wheeze sounds detected by a commercial monitor and lung function measurements obtained through spirometry tests. Participants will undergo wheeze monitoring before and during spirometry assessments, and they will complete symptom questionnaires to provide additional context. The study seeks to determine if airflow obstruction metrics correlate with wheeze scores, potentially enhancing the understanding of respiratory conditions like asthma and COPD.
Who should consider this trial
Good fit: Ideal candidates include consenting adults aged 18-95 who are patients at University Hospitals Birmingham attending for routine lung function testing.
Not a fit: Patients who are contraindicated for spirometry, cannot consent, or have restrictive lung disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the accuracy of asthma and COPD assessments, leading to better management of these conditions.
How similar studies have performed: While the specific approach of using a wheeze monitor in this context may be novel, similar studies have explored the relationship between acoustic signals and lung function with varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consenting adult (aged 18-95) University Hospitals Birmingham patient's attending the Lung Function and Sleep Department (LF\&S) routinely as part of their standard clinical management pathway for Lung Function testing that includes Spirometry assessments. * All patients irrespective of condition will be approached to participate. Exclusion Criteria: * Subjects who are contraindicated to perform spirometry on the day of testing * Subjects who cannot speak or read English * Patients accessing non-adult services * Subjects who are unable or do not wish to consent * Patients with known or suspected restrictive lung disease
Where this trial is running
Birmingham, West Midlands
- University Hospitals Birmingham NHS Foundation Trust — Birmingham, West Midlands, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Richard Glover — University Hospitals Birmingham
- Study coordinator: Brendan Cooper, PhD
- Email: Brendan.Cooper@uhb.nhs.uk
- Phone: 01213713890
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.