Assessing Vitamin A Status in Schoolchildren in Burkina Faso
Validation and Simplification of the Retinol Isotope Dilution Technique in Burkinabe Schoolchildren
This study is trying to see if a new way to check vitamin A levels in schoolchildren in Burkina Faso works well and is easy to use at different times of the year.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 158 (estimated) |
| Ages | 7 Years to 12 Years |
| Sex | All |
| Sponsor | Institut de Recherche en Sciences de la Sante, Burkina Faso Government |
| Locations | 1 site (Bobo-Dioulasso, Bobo-Dioulasso, Houet, Région Des hauts-Bassins) |
| Trial ID | NCT06759493 on ClinicalTrials.gov |
What this trial studies
This observational study involves two cross-sectional surveys conducted among schoolchildren in Burkina Faso to validate and simplify the retinol isotope dilution technique for assessing vitamin A status. The first survey will take place at the end of the rainy season, while the second will occur during the mango season, allowing for a comparison of vitamin A levels at different times of the year. The study aims to refine this nuclear technique to enhance its accessibility for population-based evaluations and inform public health interventions regarding vitamin A deficiency.
Who should consider this trial
Good fit: Ideal candidates for this study are schoolchildren aged 7-12 years living in the study areas whose guardians consent to their participation.
Not a fit: Patients who are clinically diagnosed with vitamin A deficiency or severe malnutrition, as well as those with serious illnesses, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved methods for assessing vitamin A deficiency, ultimately enhancing public health strategies for children in Burkina Faso.
How similar studies have performed: While the retinol isotope dilution technique has been evaluated previously, this study aims to refine and simplify its application in larger populations, making it a novel approach in this context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * School children aged 7-12 years * Child's guardian or parent is willing to provide informed consent * Child's family plans to remain resident in the study areas during the study period Exclusion Criteria: * Clinical evidence of vitamin A deficiency a mis en forme : Anglais (Royaume-Uni)a mis en forme : Anglais (États-Unis)a mis en forme : Anglais (États-Unis)a mis en forme : Anglais (États-Unis) * Severe malnutrition (weight-for age Z score (WAZ) or height-for-age Z score (HAZ) \<-3 SD) * Serious illnesses including tuberculosis, symptomatic HIV infection * Child aged \<6 years or \>12 years
Where this trial is running
Bobo-Dioulasso, Bobo-Dioulasso, Houet, Région Des hauts-Bassins
- Irss-Dro — Bobo-Dioulasso, Bobo-Dioulasso, Houet, Région Des hauts-Bassins, Burkina Faso (Recruiting)
Study contacts
- Principal investigator: Augustin N. ZEBA, PhD — Institut de Recherche en Sciences de la Santé
- Study coordinator: Augustin N ZEBA, Maître de Recherche
- Email: nawidzeba@gmail.com
- Phone: +22672168697
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.