Assessing venous congestion in ICU patients on mechanical ventilation
Official title: Hepatic Doppler to Assess Venous Congestion During Invasive Mechanical Ventilation
Run by University Hospital, Brest · NCT06914336 · Data updated 2026-11-12
This study is testing how well a special ultrasound can help doctors understand and manage blood flow issues in ICU patients on breathing machines.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | University Hospital, Brest Academic / other |
| Locations | 1 site (Brest) |
| Status | Recruiting |
| Started | March 24, 2025 |
| Main results expected | October 31, 2028 |
| Study ends | October 31, 2028 |
| Registry record updated | April 6, 2025 |
| Trial ID | NCT06914336 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are ICU patients who have been intubated for more than 24 hours.
✕Probably not a fit
Patients with chronic end-stage renal disease, atrial fibrillation, cirrhosis, portal thrombosis, or those who refuse to participate will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate venous congestion in ICU patients who are undergoing invasive mechanical ventilation by using hepatic vein Doppler ultrasound. The primary focus is to measure the systolic to diastolic hepatic vein velocity ratio (S/D) and to explore its correlation with various indicators of congestion. By analyzing these relationships, the study seeks to enhance understanding of venous congestion in critically ill patients and improve management strategies.
Why it matters
Potential benefit: If successful, this study could lead to better monitoring and management of venous congestion in ICU patients, potentially improving patient outcomes.
How similar studies have gone: While this approach is novel in its specific application, similar studies using Doppler ultrasound for assessing venous congestion have shown promise in other contexts.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * intubated for more than 24 hours Exclusion Criteria: * Chronic end-stage renal disease on admission * Atrial Fibrillation * Cirrhosis * Portal thrombosis * Refusal to participate * non-opposition could not be obtained from themselves or their trusted support person in the event of incapacity * Under legal protection.
Where it's running
-
Chu Brest
Brest, France Recruiting
Study contacts
- Study coordinator: Gwenael PRAT, phD
- Email: gwenael.prat@chu-brest.fr
- Phone: 0298347181
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.