Assessing venous congestion and kidney injuries in patients with cardiogenic pulmonary edema using ultrasound
Prevalence of Venous conGestion and Its Association With Renal Injuries Evaluated by the VExUS Score On Admission With UltraSound in Patients With Cardiogenic Pulmonary Edema
This study is testing how ultrasound can help doctors see if fluid buildup in the veins is linked to kidney problems in older patients with heart-related lung issues.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de la Réunion Academic / other |
| Locations | 1 site (Saint-Denis) |
| Trial ID | NCT05881603 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the prevalence of venous congestion and its association with renal injuries in patients diagnosed with cardiogenic acute pulmonary edema (C APE). It utilizes the Venous Excess Ultrasound Score (VExUS) to assess patients upon admission. The study aims to gather data on the clinical presentation and treatment outcomes of C APE, particularly focusing on the elderly population. By analyzing ultrasound findings, the study seeks to improve understanding of the condition and its management.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are diagnosed with cardiogenic acute pulmonary edema.
Not a fit: Patients who are breastfeeding, have a history of kidney transplantation, or have known hypersensitivity to furosemide may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the diagnosis and treatment of cardiogenic pulmonary edema, potentially reducing morbidity and mortality rates.
How similar studies have performed: While the use of ultrasound in assessing venous congestion is gaining traction, this specific approach with the VExUS score is relatively novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years old * Diagnosis of cardiogenic Acute Pulmonary Edema defined by the association of clinical acute respiratory distress (current breath rate \> 25/min, indrawing, flapping of the wings of the nose, thoraco-abdominal rocking, signs of hypoxemia, signs of hypercapnia) AND signs of pulmonary overload (clinical, biological and radiological arguments). * Having given their non-objection to participation in the study (or non-objection of a loved one in an emergency context) Exclusion Criteria: * Breastfeeding in progress * Known hypersensitivity to furosemide * History of kidney transplantation * Known water and electrolyte disorder * Hepatic encephalopathy * Suspicion of obstruction in the urinary tract * Person deprived of liberty by judicial or administrative decision, minor, person subject to a measure of legal protection
Where this trial is running
Saint-Denis
- CHU de la Réunion — Saint-Denis, France (Recruiting)
Study contacts
- Study coordinator: Lucie AUZANNEAU
- Email: lucie.auzanneau@chu-reunion.fr
- Phone: 0262359949
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.