Assessing the safety of Linovera Emulsion for preventing pressure ulcers and diabetic foot ulcers

Multicenter, Long-term, Single-arm and Observational PMCF Study on the Safety of Linovera Emulsion for the Prevention of Stage 1 Pressure Ulcers, Vascular and Diabetic Foot Ulcers (PRELINEM)

Observational B. Braun Medical SA · NCT05763654

This study is testing if Linovera Emulsion can safely help adults at risk of developing pressure ulcers and diabetic foot ulcers.

Quick facts

Study typeObservational
Enrollment164 (estimated)
Ages18 Years to 99 Years
SexAll
SponsorB. Braun Medical SA Industry-sponsored
Drugs / interventionschemotherapy
Locations1 site (Vigo)
Trial IDNCT05763654 on ClinicalTrials.gov

What this trial studies

This observational study evaluates the safety and efficacy of Linovera® Emulsion in preventing Grade I pressure ulcers, vascular ulcers, and diabetic foot ulcers. It involves a proactive Post Market Clinical Follow-up (PMCF) to gather diverse safety and performance data over a six-month follow-up period. Eligible participants include adults at medium to very high risk of developing these conditions, with assessments based on various clinical parameters.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who are at medium to very high risk of developing pressure ulcers or diabetic foot ulcers.

Not a fit: Patients under 18, those with known allergies to Linovera Emulsion, or those in terminal stages of illness may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a new preventive treatment option for patients at risk of developing pressure ulcers and diabetic foot ulcers.

How similar studies have performed: Other studies have shown promising results with similar preventive approaches, indicating potential for success in this area.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Signed informed consent
* Patients with the possibility to participate during up 6 month follow-up.
* At least one of these criteria:
* Patients with medium, high or very high risk of amputation due to a vascular or diabetic foot illness.
* Patients with medium, high or very high risk of developing a pressure ulcer due to any neuropathic foot pathology
* Patients with medium, high or very high risk of developing a pressure ulcer following Braden Scale.

Exclusion Criteria:

* Age \< 18 years
* Known allergies and/or hypersensitivity to any component of Linovera® Emulsion.
* Any medical or psychological disorder that, in the investigator's opinion, may interfere with the patient's ability to give informed consent and comply with the study procedures.
* Patients in the terminal stage or receiving chemotherapy.
* Patients with more than 3 active pressure ulcers.

Where this trial is running

Vigo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pressure Ulcer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.