Assessing the safety and effectiveness of a new approach to coronary procedures

A Prospective Registry to Assess the Safety and Efficacy of Distal Radial Approach (SAFE-BOX)

Observational Yonsei University · NCT05776550

This study is testing a new way to perform heart procedures through the wrist to see if it makes patients feel more comfortable and recover faster compared to the usual method.

Quick facts

Study typeObservational
Enrollment3600 (estimated)
Ages20 Years and up
SexAll
SponsorYonsei University Academic / other
Locations1 site (Yongin, Gyeonggi-do)
Trial IDNCT05776550 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the safety and efficacy of the distal radial approach for coronary artery procedures. It focuses on the advantages of this technique, such as reduced bleeding and increased patient comfort, allowing for immediate mobility post-procedure. The study will involve a prospective registry of patients over 20 years old who require coronary angiography or intervention and have a palpable distal radial artery. The research will compare outcomes with traditional radial artery approaches to determine the benefits of this newer method.

Who should consider this trial

Good fit: Ideal candidates are patients over 20 years old requiring coronary angiography or intervention with a palpable distal radial artery.

Not a fit: Patients with a non-palpable or too small distal radial artery, pregnant women, or those deemed inappropriate by the researcher may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance patient comfort and safety during coronary procedures.

How similar studies have performed: While the distal radial approach is gaining attention, this specific study is among the early efforts to systematically assess its safety and efficacy.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients over 20 years of age
2. Patients requiring coronary angiography or intervention
3. Patients with palpable distant radial artery

Exclusion Criteria:

1. Patients with distant radial artery too small or not palpable
2. Pregnant women
3. Patients not appropriate for the researcher to judge

Where this trial is running

Yongin, Gyeonggi-do

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions SafetyEfficacy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.