Assessing the precision and reliability of DXA and pQCT scanners
Official title: Precision and Reliability of Dual X-ray Absorptiometry (DXA) Testing
Run by Penn State University · NCT03621306 · Data updated 2026-11-12
This study is trying to see how accurately different bone scanning machines measure bone density and body composition in healthy adults to improve their reliability.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | Penn State University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (University Park, Pennsylvania) |
| Status | Recruiting |
| Started | June 16, 2008 |
| Main results expected | December 31, 2028 |
| Study ends | December 31, 2028 |
| Registry record updated | July 6, 2026 |
| Trial ID | NCT03621306 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy adults aged 18-40 or over 40 years.
✕Probably not a fit
Patients who are pregnant, have certain medical devices, or weigh over 450 lbs may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the precision of various imaging technologies, specifically the GE Lunar iDXA, Hologic Horizon W DXA scanner, and Stratec pQCT scanner, in measuring bone mineral density and body composition. It aims to determine variability in test results due to factors such as technician differences, equipment used, and patient positioning. The study will also establish a database of test results to enhance understanding of these imaging methods' strengths and limitations. By focusing on both inanimate objects and healthy adults, the research seeks to improve the reliability of these important diagnostic tools.
Why it matters
Potential benefit: If successful, this study could lead to more accurate assessments of bone health and body composition, improving patient care in conditions like osteoporosis and obesity.
How similar studies have gone: Other studies have shown success in assessing the precision of DXA and pQCT technologies, indicating that this approach is supported by existing research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Healthy adults of two age groups, 1) aged 18-40 or 2) aged \>40yr. Exclusion Criteria: 1. for females, being pregnant 2. Having had X-ray procedures using contrast material in the previous 3 days 3. Having medical devices that interfere with scan accuracy 4. Wearing external metal objects that cannot be removed 5. Having internal metal objects 6. Body mass of \> 450 lbs. 7. Having ostomies
Where it's running
-
Women's Health and Exercise Laboratories, The Pennsylvania State University
University Park, Pennsylvania, United States Recruiting
Study contacts
- Principal investigator: Mary Jane De Souza, PhD — Penn State
- Study coordinator: Mary Jane De Souza, PhD
- Email: mjd34@psu.edu
- Phone: 814-863-0045
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.