Assessing the precision and reliability of DXA and pQCT scanners
Precision and Reliability of Dual X-ray Absorptiometry (DXA) Testing
This study is trying to see how accurately different bone scanning machines measure bone density and body composition in healthy adults to improve their reliability.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Penn State University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (University Park, Pennsylvania) |
| Trial ID | NCT03621306 on ClinicalTrials.gov |
What this trial studies
This study evaluates the precision of various imaging technologies, specifically the GE Lunar iDXA, Hologic Horizon W DXA scanner, and Stratec pQCT scanner, in measuring bone mineral density and body composition. It aims to determine variability in test results due to factors such as technician differences, equipment used, and patient positioning. The study will also establish a database of test results to enhance understanding of these imaging methods' strengths and limitations. By focusing on both inanimate objects and healthy adults, the research seeks to improve the reliability of these important diagnostic tools.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged 18-40 or over 40 years.
Not a fit: Patients who are pregnant, have certain medical devices, or weigh over 450 lbs may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate assessments of bone health and body composition, improving patient care in conditions like osteoporosis and obesity.
How similar studies have performed: Other studies have shown success in assessing the precision of DXA and pQCT technologies, indicating that this approach is supported by existing research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Healthy adults of two age groups, 1) aged 18-40 or 2) aged \>40yr. Exclusion Criteria: 1. for females, being pregnant 2. Having had X-ray procedures using contrast material in the previous 3 days 3. Having medical devices that interfere with scan accuracy 4. Wearing external metal objects that cannot be removed 5. Having internal metal objects 6. Body mass of \> 450 lbs. 7. Having ostomies
Where this trial is running
University Park, Pennsylvania
- Women's Health and Exercise Laboratories, The Pennsylvania State University — University Park, Pennsylvania, United States (Recruiting)
Study contacts
- Principal investigator: Mary Jane De Souza, PhD — Penn State
- Study coordinator: Mary Jane De Souza, PhD
- Email: mjd34@psu.edu
- Phone: 814-863-0045
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.