Assessing the KeriFlex® silicone joint implant for arthritis treatment

Effectiveness and Safety of the Silicone Joint Implant KeriFlex® and of Its Associated Instruments in the Treatment of MCP and PIP Arthritis: Post Market Clinical Follow up

Observational Keri Medical SA · NCT06546345

This study is testing how well the KeriFlex® silicone joint implant works and is safe for people with different types of arthritis who are getting joint replacement surgery.

Quick facts

Study typeObservational
Enrollment86 (estimated)
Ages18 Years and up
SexAll
SponsorKeri Medical SA Industry-sponsored
Locations3 sites (Besançon and 2 other locations)
Trial IDNCT06546345 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the performance and safety of the KeriFlex® silicone joint implant used in arthroplasty for patients with rheumatoid arthritis, degenerative arthritis, or traumatic arthritis. The study will monitor both short-term and long-term outcomes related to the implant's lifecycle, ensuring adherence to the manufacturer's instructions. By collecting data from patients undergoing this procedure, the study seeks to provide insights into the effectiveness and safety of the KeriFlex® implant.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older who are scheduled for arthroplasty of the metacarpophalangeal or proximal interphalangeal joint using a KeriFlex® implant.

Not a fit: Patients who are pregnant, have significant physical activity involving the treated joint, or have contraindications to surgery will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance treatment options for patients with arthritis by providing a safer and more effective joint implant.

How similar studies have performed: While this study focuses on a specific implant, similar observational studies have shown success in evaluating joint implants, suggesting a potential for valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients (age ≥ 18 years)
* Patients who are going to undergo arthroplasty of the metacarpophalangeal or proximal interphalangeal joint using a KeriFlex® implant in accordance with the instructions for use and the labelling in force.
* Patients with rheumatoid arthritis, osteoarthritis or post-traumatic osteoarthritis

Exclusion Criteria:

* Pregnant or breastfeeding women
* Patients with an intellectual disability who cannot follow their surgeon's instructions
* Patients with general surgery contraindications and particularly to the implantation of a KeriFlex® implant
* Patients with acute or chronic, local or systemic infections
* Metacarpal or phalanx destruction or poor bone quality preventing adequate fixation
* Muscle loss, alteration or vascular deficiency in the affected finger
* Patients with significant physical activity involving treated joint
* Children, young growing patients with open epiphyses

Where this trial is running

Besançon and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Rheumatoid ArthritisDegenerative ArthritisTraumatic Arthritis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.