Assessing the impact of ureteral rest duration before surgery for ureteral stricture

Study to Assess Duration of Ureteral Rest Prior to Ureteral Reconstruction Surgery

Observational Northwestern University · NCT06384079

This study is trying to see if the length of time a ureter is rested before surgery can affect how long the ureteral strictures are in adults who are about to have surgery for this condition.

Quick facts

Study typeObservational
Enrollment25 (estimated)
Ages18 Years and up
SexAll
SponsorNorthwestern University Academic / other
Locations1 site (Chicago, Illinois)
Trial IDNCT06384079 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate how the duration of ureteral rest, defined as the time from switching from a ureteral stent to a percutaneous nephrostomy, affects the length of ureteral strictures prior to undergoing ureteral reconstruction surgery. Participants will be adults who are scheduled for this type of surgery and have consented to the study. The study will involve the use of antegrade and retrograde pyelograms to gather relevant data on stricture length. The findings could provide insights into optimal pre-surgical management for patients with ureteral strictures.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old who are undergoing ureteral reconstruction surgery for ureteral stricture.

Not a fit: Patients under 18 years of age or those unable to provide informed consent may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help optimize pre-surgical management and improve surgical outcomes for patients with ureteral strictures.

How similar studies have performed: While this approach is observational and may not have been extensively tested, similar studies have shown the importance of pre-surgical management in improving outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* \>18 years of age
* Undergoing ureteral reconstruction surgery for ureteral stricture with conversion of an indwelling stent to a percutaneous nephrostomy tube for ureteral rest
* Willing to sign informed consent form
* Able to read and understand informed consent form

Exclusion Criteria:

* \<18 years of age
* Inability to provide informed consent
* Members of vulnerable patient populations

Where this trial is running

Chicago, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ureteral Stricture
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.