Assessing the impact of personality traits and stress on dementia conversion
Multifactorial Approach to Dementia. Multicentric Study
This study is trying to see if having certain personality traits and experiencing stress can increase the chances of healthy people over 50 developing dementia.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 450 (estimated) |
| Ages | 45 Years to 80 Years |
| Sex | All |
| Sponsor | Universidad Atlantida Academic / other |
| Locations | 1 site (Buenos Aires, Outside U.S. And Canada) |
| Trial ID | NCT05923307 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate how narcissistic personality disorder and life stressful events contribute to the conversion rate to dementia. It employs a three-tiered approach, including retrospective assessments of dementia patients and prospective follow-ups of healthy individuals over 50. Participants will undergo comprehensive neurocognitive evaluations, brain imaging, laboratory analyses, and sociodemographic profiling to identify potential risk factors for dementia. The study seeks to enhance understanding of modifiable risk factors that could inform future interventions.
Who should consider this trial
Good fit: Ideal candidates include healthy individuals over 50 years old and patients with a confirmed diagnosis of dementia.
Not a fit: Patients with severe comorbid conditions that prevent them from completing assessments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for preventing dementia in at-risk populations.
How similar studies have performed: Previous studies have explored risk factors for dementia, but the specific focus on personality traits as mediators is less common, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: research line 3 * healthy subjects over 50 years of age. * diagnosis of dementia should be made according to DSM V criteria. * Diagnoses made by operationalised criteria for dementia Exclusion Criteria: * Participants excluded if declined participation, died or withdrew from the study * unable to perform the assessments due to other co-morbid conditions * were too visually impaired to complete cognitive assessments. in research lines 1 and 2 inclusion criteria subjects with confirmed diagnosis of dementia * putative narcisistic personality disorder * no age limit
Where this trial is running
Buenos Aires, Outside U.S. And Canada
- universidad Atlantida — Buenos Aires, Outside U.S. And Canada, Argentina (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.