Assessing the effects of Humira in adults with Pyoderma Gangrenosum

Post-marketing Observational Study for Humira in Participants Diagnosed With Pyoderma Gangrenosum (PG)

Observational AbbVie · NCT04750213

This study is testing how well Humira works and what side effects it might cause in adults with Pyoderma Gangrenosum.

Quick facts

Study typeObservational
Enrollment60 (estimated)
Ages15 Years and up
SexAll
SponsorAbbVie Industry-sponsored
Drugs / interventionsAdalimumab
Locations46 sites (Nagoya shi, Aichi and 45 other locations)
Trial IDNCT04750213 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the incidence of adverse events and changes in disease state among adult patients diagnosed with Pyoderma Gangrenosum (PG) who are being treated with Humira (Adalimumab). Approximately 60 participants will be monitored across 60 sites in Japan, receiving Humira as prescribed by their physicians. Regular medical assessments and interviews will be conducted to track side effects and treatment efficacy. The study focuses on understanding the safety profile of Humira in this specific patient population.

Who should consider this trial

Good fit: Ideal candidates for this study are adults diagnosed with Pyoderma Gangrenosum who have been prescribed Humira within the last 14 days.

Not a fit: Patients who have previously been treated with Humira for Pyoderma Gangrenosum will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the safety and effectiveness of Humira for treating Pyoderma Gangrenosum, potentially improving patient outcomes.

How similar studies have performed: While Humira is the only approved treatment for Pyoderma Gangrenosum in Japan, this study's focus on adverse events is relatively novel and has not been extensively tested in similar contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed with Pyoderma Gangrenosum (PG).
* Have been prescribed Humira for PG treatment within 14 days.

Exclusion Criteria:

- Have Pyoderma Gangrenosum (PG) in previous treatment with Humira.

Where this trial is running

Nagoya shi, Aichi and 45 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pyoderma GangrenosumHumiraAdalimumab
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.