Assessing the effectiveness of foscarbidopa/foslevodopa in adults with advanced Parkinson's disease

Effectiveness aNd Use of fosleVOdopa-foscarbidopa in Advanced Parkinson Disease in Real Life Setting

Observational AbbVie · NCT06639620

This study is testing if a new treatment called foscarbidopa/foslevodopa can help adults with advanced Parkinson's disease feel better in a real-world setting.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorAbbVie Industry-sponsored
Locations29 sites (Strasbourg, Alsace and 28 other locations)
Trial IDNCT06639620 on ClinicalTrials.gov

What this trial studies

This observational study evaluates the effectiveness and adverse events of foscarbidopa/foslevodopa in treating adult participants with advanced Parkinson's disease in a real-world clinical setting. Approximately 200 participants will be enrolled across 30 sites in France, receiving subcutaneous infusions of the drug as prescribed by their physicians. Participants will be monitored for up to 12 months, attending regular visits at hospitals or clinics without any additional burden from the study.

Who should consider this trial

Good fit: Ideal candidates are adults with advanced Parkinson's disease experiencing motor complications that are not adequately controlled by their current therapy.

Not a fit: Patients with contraindications to foscarbidopa/foslevodopa or a Mini Mental State Examination score below 24 may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the real-world effectiveness of foscarbidopa/foslevodopa for managing advanced Parkinson's disease symptoms.

How similar studies have performed: While foscarbidopa/foslevodopa is an approved treatment outside the US, this study's observational approach in a real-world setting is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants with advanced Parkinson disease with motor complications insufficiently controlled by current therapy
* Participants eligible for foscarbidopa / foslevodopa according to French label \& regulation.
* Treatment initiation decision prior to and independently from study enrolment

Exclusion Criteria:

* Participants with any contraindication to foscarbidopa / foslevodopa.
* Participants with Mini mental state examination (MMSE) score \< 24

Where this trial is running

Strasbourg, Alsace and 28 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Advanced Parkinson DiseaseAdvanced Parkinson diseaseFoscarbidopa/ foslevodopaABBV-951LDp/CDp
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.