Assessing the DD4 Questionnaire's Role in Predicting Depressive Relapse After Hospitalization

Predictive Value of the DD4 Questionnaire on Depressive Relapse After Hospitalization

GCS Ramsay Santé pour l'Enseignement et la Recherche · NCT05678907

This study is trying to see if a questionnaire can help predict if people who were hospitalized for depression will have a relapse after they leave the hospital.

Quick facts

Study typeObservational
Enrollment150 (estimated)
Ages18 Years and up
SexAll
SponsorGCS Ramsay Santé pour l'Enseignement et la Recherche (other)
Locations1 site (La Roche-Blanche)
Trial IDNCT05678907 on ClinicalTrials.gov

What this trial studies

This observational study examines the predictive value of the DD4 questionnaire in patients who have been hospitalized for a depressive episode. It involves a review of medical records and follow-up assessments conducted three months post-discharge to evaluate the likelihood of depressive relapse. The study focuses on patients who are considered in remission at the time of follow-up, utilizing data collected during their hospitalization and subsequent evaluations.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who have been hospitalized for a depressive episode and are in remission at the time of follow-up.

Not a fit: Patients with bipolar depression, psychotic disorders, or those unable to complete a self-assessment questionnaire may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify patients at risk of depressive relapse, allowing for timely interventions.

How similar studies have performed: While similar observational studies have been conducted, the specific use of the DD4 questionnaire in this context is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient 18 years of age or older, having been informed of the research
* Patient hospitalized at the Auzon Clinic for a characterized depressive episodé (isolated episode or recurrent depressive disorder)
* Discharged from hospitalization
* Considered in remission (total or partial) and with a MADRS score \< 20

Exclusion Criteria:

* Patient hospitalized for \< 15 days
* Patient with bipolar depression
* Patient with a psychotic disorder
* Patient using narcotics with a "moderate to severe" severity
* Patient previously included in this study
* Patient under court protection, guardianship or curatorship
* Patient unablé to respond correctly to a depression self-assessment questionnaire

Where this trial is running

La Roche-Blanche

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Depressive Episode

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.