Assessing testicular function and semen quality in young male cancer survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the testicular function and semen quality in male survivors of childhood and adolescent cancer who are now adults. Participants will include men aged 18 to 50 who received chemotherapy or radiotherapy for cancer diagnosed before age 18 and have been in remission for at least two years. The study will compare their testicular function with that of age-matched controls from a premarital check-up clinic. Data will be collected through hormonal profiling, semen analysis, and questionnaires.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Men who have received chemotherapy and/ or radiotherapy for cancer diagnosed when they were \< 18 years old.
* \> 18 years old to 50 years old
* Cancer in remission for at least 2 years

Exclusion Criteria:

* Unable to ejaculate by masturbation to provide semen samples
* Cryptorchidism, testicular cancer, history of vasectomy
* On testosterone replacement therapy
* Refusal to join the study

Where it's running

• Queen Mary Hospital
  Hong Kong, China Recruiting

Study contacts

• Study coordinator: Jennifer Ko
• Email: jenko@hku.hk
• Phone: 22554647

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.