Assessing swallowing function changes in oral cancer patients
Using High Resolution Impedance Manometry (HRIM) Combined With Videofluoroscopic Swallow Study (VFSS) to Investigate the Changes of Swallowing Function in Oral Cancer Patients
This study looks at how swallowing changes for people with tongue cancer before and after surgery to better understand their difficulties.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 20 Years to 80 Years |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT04862637 on ClinicalTrials.gov |
What this trial studies
This observational study investigates changes in swallowing function among patients diagnosed with tongue cancer. It utilizes videofluoroscopy (VFSS) and high-resolution impedance manometry (HRIM) to evaluate swallowing difficulties before and after surgical interventions. The aim is to gather evidence on how oral cancer affects swallowing, which is currently limited. Patients will be monitored for swallowing discomfort during the study.
Who should consider this trial
Good fit: Ideal candidates are patients diagnosed with tongue cancer who are scheduled for elective oral cancer surgery.
Not a fit: Patients with major underlying diseases, coagulopathy, pregnancy, or those unable to comply with study requirements may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management and rehabilitation strategies for patients with swallowing difficulties due to oral cancer.
How similar studies have performed: While there is limited evidence on swallowing changes in tongue cancer patients, similar studies using VFSS and HRIM have shown promise in assessing dysphagia in other populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients elective received oral cancer surgery and suitable to receive mandibular-lip split or pull-through resection surgeries Exclusion Criteria: * 1. patients had major underlying disease, ex: heart, brain, lung, liver disease * 2. coagulopathy * 3.pregnancy * 4. the patients could not have good compliance
Where this trial is running
Taipei
- National Taiwan University Hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Study coordinator: Shih-Jung Cheng, MD,PhD
- Email: sjcheng56@ntu.edu.tw
- Phone: 0223123456
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.