Assessing speech disorders in patients treated for oral or oropharyngeal cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate speech intelligibility in patients who have undergone treatment for oral or oropharyngeal cancer. It utilizes an acoustic-phonetic decoding task to objectively assess speech production and perception, bridging the gap between the two. The study hypothesizes that automatic processing of this task will provide reliable diagnostic insights into oropharyngeal deficits. Participants will be assessed based on their ability to produce isolated pseudo-words, with scores correlated to anatomical and functional speech deficits.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged at least 18 years old and benefiting from a social security scheme
* Native French-speaking patients
* Patients treated for cancer of the oral cavity or oropharynx (surgical and / or radiotherapy and / or chemotherapy treatment)
* Patients in clinical remission for at least 6 months (chronic nature and stability of the disorders)
* All tumor sizes according to the tumor (T), node (N), and metastasis (M) categories (TNM classification) (T1 to T4)
* Patients with a perceptible speech disorder in a conversational situation or not (to allow the determination of fine deficits)
* Patients who do not object to carrying out the research

Exclusion Criteria:

* Patients with an associated pathology potentially responsible for speech or fluency disorders (joint, speech and language disorders of developmental, organic or functional origin, voice disorders of organic or functional origin, stammering , stammering, fluency disturbances, speech disturbances of neurological origin)
* Patients reporting an auditory complaint and not having a hearing aid
* Inability to provide the person with enlightened information and to ensure the subject's compliance because of impaired physical and / or psychological health,
* Patients participating in another research including an exclusion period still in progress.

Where it's running

• AP- H Marseille - Hôpital de la Conception
  Marseille, France Recruiting
• University Hospital Toulouse
  Toulouse, France Recruiting
• Institut universitaire du Cancer de Toulouse - Oncopole
  Toulouse, France Not yet recruiting

Study contacts

• Principal investigator: Clémence DEVOUCOUX — University Hospital, Toulouse
• Study coordinator: Clémence DEVOUCOUX
• Email: devoucoux.c@chu-toulouse.fr
• Phone: 06.50.72.24.85

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.