Assessing social cognition in children with autism using MRI and eye tracking

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance the assessment of social cognition in children with Autism Spectrum Disorders (ASD) by utilizing a novel approach that combines MRI and eye tracking technology. By creating video-based visual percepts that closely mimic real-life social interactions, the study seeks to better understand how joint attention develops over time in autistic children. The research will longitudinally explore the neurodevelopmental aspects of social cognition, addressing a gap in existing literature regarding the influence of age on joint attention perception in individuals with ASD.

Why it matters

Who can join: the full rules

Inclusion Criteria:

For the group of people with Autism Spectrum Disorders (experimental group):

* Age between 10 to 20 years old
* Diagnosis of ASD (CARS) ≥ 30 performed at inclusion
* IQ test evaluation (regardless of the result) performed by a trained psychologist
* Obtaining informed oral and written consent after appropriate information
* Obtaining informed oral and written consent from the legal guardian after information
* Be affiliated with social security
* No contraindication to magnetic resonance imaging

For the TD (Typical Development) group of people (control group):

* Age between 10 to 20 years old
* Diagnosis of ASD (CARS) \<30 performed at inclusion
* IQ test evaluation (regardless of the result) performed by a trained psychologist
* Obtaining informed oral and written consent after appropriate information
* Obtaining informed oral and written consent from the legal guardian after information
* Be affiliated with social security
* No contraindication to magnetic resonance imaging

Exclusion Criteria:

For all groups:

* Age outside the range 10 to 20 years
* Person with a contraindication to MRI (including claustrophobia, pace maker, neurosurgical clips, vascular clips, heart valves, ventriculoperitoneal valves, cochlear implant, neurostimulator, intraocular metal shards, joint prosthesis, etc.)
* Person suffering from major obesity (\> 140 kg) not allowing him to enter the tunnel of the MRI machine (diameter \<70cm)
* Pregnant or breastfeeding woman
* Person under guardianship or guardianship or deprived of liberty by a judicial or administrative decision

For TD people (control group):

* Person with psychiatric disorders such as attention disorder with or without hyperactivity, depression, bipolar disorder and schizophrenia.
* Person with a neurological history such as epilepsy and / or neurovascular accident.

Where it's running

• CHU Amiens Picardie
  Amiens, Picardie, France Recruiting

Study contacts

• Study coordinator: Jean-Marc Constans, Pr
• Email: constans.jean-marc@chu-amiens.fr
• Phone: 03 22 08 75 15

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.