Assessing risk factors and outcomes in patients with coronary chronic total occlusion

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the risk factors and long-term outcomes of patients suffering from coronary chronic total occlusion (CTO) who are treated either with percutaneous coronary intervention or medical management. It focuses on understanding how various baseline characteristics and treatment modalities influence the prognosis of CTO patients, who typically face worse outcomes compared to those without CTO. The study will involve collecting clinical data and blood samples to identify factors that may contribute to the development of coronary collateral formation and overall patient outcomes. Conducted at a single center, this research seeks to enhance clinical decision-making for managing coronary artery disease.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18 years; Patients with angina or silent ischemia and documented ischemia; Patients with CTO ≥ 3months

Exclusion Criteria:

* eGFR\<15mL/(min·1.73m2); Chronic heart failure with NYHA grade ≥3; Had a history of coronary artery bypass grafting; Had received a percutaneous coronary intervention within the prior 3 months; Malignant tumor or immune system disorders; Pulmonary heart disease

Where it's running

• Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
  Shanghai, China Recruiting

Study contacts

• Study coordinator: Fenghua Ding, PhD, MD
• Email: ruijindfh@126.com
• Phone: 0086 021 64370045

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.