Assessing Quality of Life in Elderly Patients with Low Grade Non-Hodgkin Lymphoma
Quality Of Life On Elderly Patients With Low Grade Non-Hodgkin Lymphoma Treated With Immunotherapy Or Immunochemotherapy And/Or Radiotherapy: An Observational Prospective Study Of The Fondazione Italiana Linfomi
This study looks at how the quality of life changes for older patients with low-grade non-Hodgkin lymphoma during and after their treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 70 Years and up |
| Sex | All |
| Sponsor | Fondazione Italiana Linfomi - ETS Academic / other |
| Drugs / interventions | immunotherapy |
| Locations | 20 sites (Alessandria, Alessandria and 19 other locations) |
| Trial ID | NCT05524298 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the changes in quality of life (QoL) among elderly patients diagnosed with low-grade non-Hodgkin lymphoma during their clinical management. It will involve a prospective, multicenter approach, enrolling 150 patients aged 70 and older who have a confirmed diagnosis of indolent B cell non-Hodgkin lymphoma. Participants will undergo a Comprehensive Geriatric Assessment and will have their QoL assessed at baseline, after treatment, and one year post-therapy. The study seeks to identify key factors influencing QoL throughout the treatment process.
Who should consider this trial
Good fit: Ideal candidates for this study are elderly patients aged 70 years and older with a histologically confirmed diagnosis of indolent B cell non-Hodgkin lymphoma who are candidates for treatment.
Not a fit: Patients who have previously received treatment for lymphoma or those under 70 years of age may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into improving the quality of life for elderly patients undergoing treatment for low-grade non-Hodgkin lymphoma.
How similar studies have performed: While this study focuses on a specific patient demographic, similar studies assessing quality of life in cancer patients have shown promising results, indicating that understanding QoL can lead to improved patient care.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Local histological diagnosis of indolent B cell non-Hodgkin lymphoma: follicular lymphoma, marginal zone lymphoma (nodal, MALT (Mucosa-Associated Lymphoid Tissue), splenic), lymphoplasmacytic lymphoma/ Waldenström macroglobulinemia) * Age ≥ 70 years * Patient candidates to receive treatment for lymphoma * Patient previously untreated for lymphoma * Evaluation of Comprehensive Geriatric Assessment at baseline * Ability to provide informed consent: subject understands and voluntarily signs an informed consent form approved by an IEC (Independent Ethics Committee), prior to registration into the study Note: Patient treated in the context of a clinical trial is admitted Exclusion Criteria: * none
Where this trial is running
Alessandria, Alessandria and 19 other locations
- S.C. Ematologia - A.O. SS. Antonio e Biagio e Cesare Arrigo — Alessandria, Alessandria, Italy (Recruiting)
- Clinica di Ematologia - A.O.U. Ospedali Riuniti — Ancona, Italy, Italy (Recruiting)
- U.O.C. Ematologia - IRCCS Istituto Tumori Giovanni Paolo II — Bari, Italy, Italy (Recruiting)
- Ematologia - ASST Spedali Civili di Brescia — Brescia, Italy, Italy (Recruiting)
- Ematologia - Ospedale di Castelfranco Veneto — Castelfranco Veneto, Italy, Italy (Recruiting)
- U.O.C. di Ematologia - Azienda Ospedaliera Universitaria Policlinico - Rodolico S. Marco — Catania, Italy, Italy (Recruiting)
- Unità funzionale di Ematologia - Azienda Ospedaliera Universitaria Careggi — Florence, Italy, Italy (Recruiting)
- S.C. Ematologia - Azienda Ospedali Riuniti Papardo-Piemonte — Messina, Italy, Italy (Recruiting)
- Unitа Linfomi - Dipartimento Oncoematologia, Istituto Scientifico San Raffaele — Milan, Italy, Italy (Recruiting)
- S.C. Ematologia - ASST Grande Ospedale Metropolitano Niguarda — Milan, Italy, Italy (Recruiting)
- Ematologia - A.O.U. Policlinico Giaccone — Palermo, Italy, Italy (Recruiting)
- Divisione di Ematologia - A.O. Ospedali Riuniti Villa Sofia-Cervello — Palermo, Italy, Italy (Recruiting)
- U.O. Ematologia - Ospedale Guglielmo da Saliceto — Piacenza, Italy, Italy (Recruiting)
- Ematologia - Azienda Unitа Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova — Reggio Emilia, Italy, Italy (Recruiting)
- U.O. di Ematologia - Ospedale degli Infermi di Rimini — Rimini, Italy, Italy (Recruiting)
- Ematologia,Trapianto cellule staminali, Medicina Trasfusionale e Terapia cellulare -Policlinico Universitario Campus Bio-Medico — Roma, Italy, Italy (Recruiting)
- U.O.C. Ematologia - A.O.U. Senese — Siena, Italy, Italy (Recruiting)
- U.O.C. Ematologia - Ospedale di Circolo — Varese, Italy, Italy (Recruiting)
- Ospedale San Bassiano - AULSS7 Pedemontana - UOC Oncoematologia — Bassano del Grappa, Vicenza, Italy (Recruiting)
- Divisione di Oncologia e dei Tumori immuno-correlati - IRCCS Centro di Riferimento Oncologico di Aviano — Aviano, Italy (Recruiting)
Study contacts
- Principal investigator: Salvatrice Mancuso — Ematologia - A.O.U. Policlinico Giaccone, Palermo
- Study coordinator: Marina Cesaretti
- Email: mcesaretti@filinf.it
- Phone: +39 059 9769913
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.