Assessing psychological and psychiatric factors in epilepsy surgery candidates
Official title: Psychological and Psychiatric Assessment in Patients Eligible for Epilepsy Surgery
Run by Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · NCT06792383 · Data updated 2026-11-12
This study looks at how surgery for drug-resistant epilepsy affects the mental health and quality of life of patients, comparing those who have surgery right away with those who wait.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 180 (estimated) |
| Sponsor | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta Academic / other |
| Locations | 1 site (Milan) |
| Status | Recruiting |
| Started | December 2, 2020 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | February 12, 2026 |
| Trial ID | NCT06792383 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 or older with drug-resistant focal epilepsy who are eligible for epilepsy surgery.
✕Probably not a fit
Patients with significant cognitive or psychiatric disorders that hinder their ability to participate in assessments will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the socio-demographic, clinical, psychological, and psychiatric characteristics of patients with drug-resistant focal epilepsy who are eligible for surgery. It will track changes in these parameters over time, focusing on quality of life, psychiatric symptoms, and stigma perception. The study will involve two groups: one undergoing surgery immediately and another waiting for further evaluations. Data will be collected at multiple time points to assess the impact of surgery on these factors.
Why it matters
Potential benefit: If successful, this study could enhance understanding of the psychological aspects of epilepsy surgery, potentially improving patient outcomes and quality of life.
How similar studies have gone: While there have been studies on epilepsy surgery outcomes, this specific focus on psychological and psychiatric assessments in a longitudinal framework is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 or older at the time of enrollment; * Patients with drug-resistant focal epilepsy followed at the Institute for at least 6 months; * Patients with drug-resistant focal epilepsy eligible for epilepsy surgery; * Patients capable of providing informed consent to participate in the study and for the processing of personal data. Exclusion Criteria: * Patients with evident and/or diagnosed cognitive or psychiatric disorders that prevent participation in an interview, proper understanding of informed consent, or completion of questionnaires.
Where it's running
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Foundation IRCCS Carlo Besta Neurological Institute
Milan, Italy Recruiting
Study contacts
- Principal investigator: Marco de Curtis, MD — Clinical and Experimental Epileptology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via G. Celoria 11, 20133 Milano, Italy
- Study coordinator: Rui Quintas, PsyD
- Email: rui.quintas@istituto-besta.it
- Phone: +39 02 2394
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Early add-on cenobamate for adults with focal epilepsy in France, Germany, and Spain
This study will see if adding cenobamate early as an extra medicine helps adults with focal epilepsy in France, Germany, and Spain who weren't controlled on 2–3 prior anti-seizure medicines.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.