Assessing Prognosis in Pancreatic Cancer Using Lewis Antigen and CA19-9 Tests

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical study aims to evaluate the prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) by combining the detection of Lewis antigens with the CA19-9 biomarker. It employs a prospective, multicenter design to classify patients based on their Lewis antigen status and CA19-9 levels, observing their survival outcomes. The study will also assess the sensitivity and specificity of Lewis antigen detection in both pancreatic cancer patients and non-cancer subjects. By analyzing the relationship between Lewis subtypes, age, and overall survival, the study seeks to enhance prognostic accuracy for pancreatic cancer.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Voluntarily enrolled, regardless of gender, aged ≥ 18 and ≤ 75 years old, and the patient can understand and is willing to sign an informed consent form;
2. ECOG 0-2
3. Pathologically confirmed as pancreatic ductal adenocarcinoma; Or confirmed by pathology and clinical examination as pancreatic ductal adenocarcinoma.
4. Willing to accept routine CA19-9 testing, Lewis antigen sample collection and testing (2-3ml), and follow-up Non pancreatic cancer subjects enrolled in this study must meet all the following criteria

1\. Voluntary enrollment, regardless of gender, age ≥ 18 years, ≤ 75 years old, and the patient can understand and is willing to sign an informed consent form 2. Willing to accept Lewis antigen sample collection and testing (2-3ml)

Exclusion Criteria:

1. Suffering from the second or double primary malignant tumor besides pancreatic cancer at the same time
2. Patients with pancreatic cancer who cannot trace the specific anti-cancer treatment plan
3. HIV positive
4. Other situations that researchers believe need to be excluded

Where it's running

• Shanghai General Hospital
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Long Jiang, MD
• Email: jiang.long@shgh.cn
• Phone: 18017317460

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.