Assessing pancreas changes during pregnancy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The MAMA study is a prospective cohort study that investigates how pancreas size changes during pregnancy in women and their infants, particularly focusing on the impact of maternal diabetes. It will follow pregnant women aged 18-54 who are under 14 weeks gestation and their babies through pregnancy and one year postpartum. Participants will undergo various assessments including MRI scans, blood tests, and glucose monitoring at multiple points during and after pregnancy to gather data on pancreas size and its relationship with gestational diabetes and infant development.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pregnant women, with a singleton gestation
* Age 18 - 54 years at screening
* Gestational age \< 14 weeks
* Willing to commit to 1 year postpartum follow up
* Planning to remain in geographical vicinity of Austin for 1 year after delivery

Exclusion Criteria:

* Presence of any mechanically or magnetically activated implants
* Claustrophobia
* Other contraindication for MRI
* BMI ≥ 38.0 or maximum width less than 48 cm (necessary to fit within the MRI field of view)

Where it's running

• Dell Medical School Health Discovery Building
  Austin, Texas, United States Recruiting

Study contacts

• Principal investigator: Jack Virostko, Ph.D. — University of Texas at Austin
• Study coordinator: Jack Virostko, Ph.D.
• Email: jack.virostko@austin.utexas.edu
• Phone: 512-495-5126

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.