Assessing outcomes of fat transfer for breast or chest wall reconstruction

Quantitative Assessment of Autologous Fat Transfer

Not applicable Interventional University of Chicago · NCT06343831

This study is testing if using your own fat for breast or chest wall reconstruction can improve results and satisfaction for patients over time.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment15 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Chicago Academic / other
Locations2 sites (Chicago, Illinois and 1 other locations)
Trial IDNCT06343831 on ClinicalTrials.gov

What this trial studies

This pilot study aims to evaluate the effectiveness of autologous fat transfer (AFT) for breast or chest wall reconstruction by utilizing various imaging techniques. Participants will undergo standard 2D photographs, 3D surface scanning, ultrasound, and MRI to assess changes in the breast over time. Additionally, they will complete the BREAST-QTM questionnaire to measure patient satisfaction and quality of life. The study will compare imaging results to provide a comprehensive understanding of the outcomes associated with AFT.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who are planning to undergo autologous fat transfer for breast or chest wall reconstruction.

Not a fit: Patients with active cancer, metastatic disease, or those unable to undergo MRI due to contraindications will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of patient outcomes and satisfaction following autologous fat transfer, leading to improved surgical techniques and patient care.

How similar studies have performed: While this study employs established imaging techniques, the specific combination and focus on patient-reported outcomes in the context of AFT is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Age of 18 years or older

* Planned autologous fat transfer or fat grafting reconstruction of the breast or chest wall.
* Able to provide written or electronic informed consent.
* Able to undergo MRI.

Exclusion Criteria:

* Vulnerable subjects (children, prisoners, pregnant women).
* Patients who have active cancer, metastatic disease, solid organ transplantation / immunosuppression, or autoimmune diseases.
* Unable to undergo MRI (history of metal contraindication, claustrophobia)

Where this trial is running

Chicago, Illinois and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Autologous Fat Grafting
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.