Assessing muscle changes in patients with chronic low back pain
Morphological Changes in Selected Back Muscles and Their Association With Back Extensors Strength in Subjects With Chronic Non-Specific Low Back Pain
Cairo University · NCT06071364
This study is testing how chronic low back pain affects certain back muscles and strength compared to healthy people to better understand the condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 58 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Cairo University (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06071364 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the morphological changes in specific back muscles, including the lumbar multifidus, Erector spinae, and Quadratus lumborum, in patients suffering from chronic non-specific low back pain (CNSLBP). It will compare these changes during rest and contraction against a control group of healthy individuals. The study will involve 29 subjects with CNSLBP and 29 age-matched healthy controls, utilizing ultrasonography for muscle assessment and a hand-held dynamometer to measure trunk extensor muscle strength. Additionally, functional disability will be evaluated using the Arabic version of the Oswestry disability index.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18 to 45 with chronic non-specific low back pain lasting more than three months.
Not a fit: Patients with untreated neurological or mental illnesses, recent trauma, or serious musculoskeletal problems may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of muscle morphology in CNSLBP, potentially leading to improved rehabilitation strategies.
How similar studies have performed: While this study explores a novel correlation between muscle morphology and strength in CNSLBP, previous research has focused on related aspects of low back pain, indicating potential for meaningful insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Subjects of both genders with CNSLBP (pain\> 3 months) 2. The subject's age ranged between 18 and 45. 3. waist-to-height ratio (WHtR) \< 0.5 or = 0.5 Exclusion Criteria: 1. Untreated neurological and/or mental illness 2. History of trauma in the last 6 months. 3. Sacroiliac joint pathologies. 4. Spinal fracture or dislocation. 5. Spinal instability (e.g., spondylolisthesis or retrolisthesis) 6. Sensitivity to ultrasound gel diagnosed by a medical doctor. 7. Serious musculoskeletal problems or other pathologies. 8. Previous surgery in lower limb(s) 9. Females during Pregnancy.
Where this trial is running
Cairo
- Cairo University — Cairo, Egypt (RECRUITING)
Study contacts
- Principal investigator: omnia yasser, master — Cairo University
- Study coordinator: Omnia Yasser, Master
- Email: monyyasser36@gmail.com
- Phone: 01064840245
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Chronic Non-specific Low Back Pain