Assessing lung function in patients with interstitial lung disease using CT scans
CT Quantitative Assessment of Interstitial Lung Disease Using Visual Score and Lung Densitometry Methods and Its Correlation With Pulmonary Function Tests
This study is trying to see if the changes in lung images from CT scans match up with how well patients with interstitial lung disease can breathe.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 70 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut, Asyut Governorate) |
| Trial ID | NCT05947422 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationship between high-resolution computed tomography (HRCT) findings and pulmonary function test results in patients diagnosed with interstitial lung disease (ILD). It will involve a cross-sectional prospective design at Assiut University Hospital, where consecutive patients with ILD will undergo both HRCT and spirometry tests. The study seeks to determine if changes in lung parenchyma observed on CT correlate with the patients' pulmonary function, providing insights into the disease's impact on lung health.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with interstitial lung disease who have recent CT chest images and pulmonary function test results.
Not a fit: Patients with conditions such as pregnancy, pulmonary edema, primary pulmonary hypertension, chronic obstructive pulmonary disease, or congestive heart failure may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of ILD and improve patient management by correlating imaging findings with lung function.
How similar studies have performed: While there have been studies investigating similar correlations, this specific approach focusing on HRCT and pulmonary function in ILD is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of ILD (based on clinical, radiological, and pulmonary function criteria +/- histopathological criteria). * Availability of CT chest DICOM images and pulmonary function test results (within a 2-weeks period from each other). Exclusion Criteria: * Pregnancy * Pulmonary edema. * Primary pulmonary hypertension; * Chronic obstructive pulmonary disease * Congestive heart failure
Where this trial is running
Asyut, Asyut Governorate
- Assiut University Hospital — Asyut, Asyut Governorate, Egypt (Recruiting)
Study contacts
- Principal investigator: Ramy M Ahmed, MD — Assiut University
- Study coordinator: Ramy M Ahmed, MD
- Email: ramycolor@aun.edu.eg
- Phone: +201153070865
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.