Assessing lung function and exercise capacity in COVID-19 patients

Lung Function, Exercise Capacity, and Serology Responses in Patients With COVID-19

Observational Chinese University of Hong Kong · NCT04611243

This study looks at how well people who have recovered from COVID-19 can breathe and exercise over two years, while also checking how their immune systems respond to the virus and vaccines.

Quick facts

Study typeObservational
Enrollment700 (estimated)
Ages18 Years and up
SexAll
SponsorChinese University of Hong Kong Academic / other
Locations1 site (Hong Kong)
Trial IDNCT04611243 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate lung function, exercise capacity, and quality of life in patients who have recovered from COVID-19 over a two-year period. It will also investigate the longevity of serological responses to SARS-CoV-2 and the effectiveness of different COVID-19 vaccines in generating immune responses. Participants will undergo various assessments, including lung function tests and blood sample collection, at multiple time points post-discharge. The study will include both convalescent patients and vaccinated individuals to understand the immune response dynamics.

Who should consider this trial

Good fit: Ideal candidates for this study are adults who have been discharged from the hospital after treatment for COVID-19.

Not a fit: Patients who are unwilling to participate in follow-up assessments will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into the long-term effects of COVID-19 and the effectiveness of vaccines, ultimately improving patient care and treatment strategies.

How similar studies have performed: Other studies have shown success in assessing long-term effects of COVID-19, but this study's specific approach to evaluating immune responses and exercise capacity is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria: Patients who have been discharged from hospital following treatment for COVID-19 -

Exclusion Criteria: Unwilling to be follow up

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Where this trial is running

Hong Kong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lung FunctionExercise CapacityQuality of LifeCovid19
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.