Assessing laser settings in prostate surgery

Laser Outcomes Associated With HoLEP Procedures

NA · Northwestern University · NCT06531473

This study is testing if using different laser settings during prostate surgery can make the procedure quicker and improve recovery without causing problems afterward.

Quick facts

PhaseNA
Study typeInterventional
Enrollment300 (estimated)
Ages18 Years to 89 Years
SexMale
SponsorNorthwestern University (other)
Locations1 site (Chicago, Illinois)
Trial IDNCT06531473 on ClinicalTrials.gov

What this trial studies

This study evaluates the effects of different laser frequency and wattage settings during holmium laser enucleation of the prostate (HoLEP) procedures. The researchers aim to determine if higher laser settings can significantly reduce procedural time without negative postoperative outcomes, while also exploring if lower settings can decrease irritative voiding symptoms post-surgery. The study is conducted at a high-volume practice where conventional settings are currently used, but optimal settings have yet to be established in the literature.

Who should consider this trial

Good fit: Ideal candidates are males aged 18-89 experiencing bothersome lower urinary tract symptoms due to enlarged prostates.

Not a fit: Patients with prostate measurements over 200g or those lacking decisional capacity may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced recovery times for patients undergoing prostate surgery.

How similar studies have performed: While there is limited literature on optimal laser settings for HoLEP, the study's approach is novel and aims to fill a significant gap in current knowledge.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Males 18-89 who are undergoing HoLEP for the treatment of bothersome lower urinary tract symptoms, that are typically caused by enlarged prostates

Exclusion Criteria:

* Prostates measurements over 200g
* Patients who lack decisional capacity
* Patients who are non-english speakers

Where this trial is running

Chicago, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Urologic Diseases, Prostate Obstruction

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.