Assessing knee fractures around prosthetic joints using advanced CT imaging
Assessment of Bone Displacement Under Loading Following Distal Femur Periprosthetic Fracture Repair With Weight-Bearing CT and Conventional CT
This study is testing if advanced weight-bearing CT scans can help doctors better see and treat knee fractures in patients who have had knee replacement surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 50 Years to 90 Years |
| Sex | All |
| Sponsor | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Academic / other |
| Locations | 1 site (London, Ontario) |
| Trial ID | NCT06909916 on ClinicalTrials.gov |
What this trial studies
This study focuses on patients who have undergone total knee arthroplasty (TKA) and subsequently experienced periprosthetic fractures. It aims to improve the assessment of component fixation and fracture healing through the use of weight-bearing CT scans, which can provide clearer imaging than traditional radiographs. By establishing reliable diagnostic criteria, the study seeks to enhance patient care and reduce the need for invasive revision surgeries. The increasing prevalence of TKA surgeries highlights the importance of this research in addressing potential complications and improving outcomes for patients.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 50-90 who have undergone revision surgery for a distal femur fracture around a TKA femoral component.
Not a fit: Patients who have undergone revision surgery for reasons other than distal femur fractures or those who cannot participate in weight-bearing assessments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better diagnostic standards and improved treatment options for patients with periprosthetic fractures.
How similar studies have performed: While there is limited consensus in the literature regarding the assessment of long-bone non-unions, this approach using advanced imaging techniques is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Underwent revision surgery for repair of a distal femur fracture surrounding a primary TKA femoral component using a fracture fixation plate \>1 year * Age 50-90 years * Body mass index up to 40kg/m2 * Able to provide informed consent * Able and willing to do study assessments and follow instructions Exclusion Criteria: * Does not understand English * Undergone revision surgery for any other indication * Received Intramedullary nail or distal femur replacement * Cannot independently stand on one leg in the weight-bearing CT during the inducible displacement exam
Where this trial is running
London, Ontario
- University Hospital - London Health Sciences Centre — London, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Brent Lanting, MD — Lawson Health Sciences Centre
- Study coordinator: Brent Lanting, MD
- Email: brent.lanting@lhsc.on.ca
- Phone: 519-685-8500
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.