Assessing heart rhythm issues after myocarditis in athletes
Quantification of Ventricular Arrhythmia After Myocarditis in Sportsman
This study is trying to see how heart rhythm problems affect athletes who have had myocarditis by monitoring their heart activity over a year.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Angers Government |
| Locations | 4 sites (Angers and 3 other locations) |
| Trial ID | NCT03842592 on ClinicalTrials.gov |
What this trial studies
This study evaluates the prevalence of ventricular arrhythmias in athletes who have experienced acute myocarditis. It involves a cohort of 50 patients diagnosed with myocarditis confirmed by MRI, who will undergo ECG Holter monitoring and treadmill stress testing over a one-year follow-up period. The goal is to understand how myocarditis affects heart rhythm in physically active individuals.
Who should consider this trial
Good fit: Ideal candidates are athletes with acute myocarditis confirmed by MRI and who engage in regular physical activity.
Not a fit: Patients with coronary artery disease or other forms of inflammatory cardiomyopathy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better management and monitoring strategies for athletes recovering from myocarditis.
How similar studies have performed: While there is limited data on this specific approach, studies on myocarditis and arrhythmias in athletes have shown varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * acute myocarditis, diagnosed on the association of (a) recent viral infection (upper airway, gastro-intestinal) , (b) troponin increase, and (c) chest pain AND myocarditis confirmed by cardiac magnetic resonance 2 out of 3 Lake Louise criteria, either T2 hypersignal, early enhancement or late gadolinium enhancement. * regular physical activity, recreational or competitive: \>=4 hours weekly * written informed consent Exclusion Criteria: * coronary artery disease * acute inflammatory cardiomyopathy (sarcoidosis, fulminant myocarditis, Tako Tsubo, eosinophilic myocarditis, Lyme disease) * history of myocarditis * contra-indication to cardiac MRI * patient unable to perform a treadmill stress test
Where this trial is running
Angers and 3 other locations
- Angers University Hospital — Angers, France (Recruiting)
- Brest University Hospital — Brest, France (Recruiting)
- Lariboisière University Hospital - AP-HP — Paris, France (Recruiting)
- Rennes University Hospital — Rennes, France (Recruiting)
Study contacts
- Principal investigator: Loïc BIERE, MD PhD — Department of Cardiology, University Hospital of Angers (France)
- Study coordinator: Loïc BIERE, MD PhD
- Email: lobiere@chu-angers.fr
- Phone: +33 241354854
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.