Assessing heart health and biological samples in patients with heart attacks
Cardiac MRI and Biological Samples at the Acute Phase of a Myocardial Infarction
This study is testing how heart health and biological samples from people who have had a severe heart attack can help doctors understand what affects recovery and complications.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Poitiers University Hospital Academic / other |
| Locations | 1 site (Poitiers) |
| Trial ID | NCT06278519 on ClinicalTrials.gov |
What this trial studies
This study focuses on patients experiencing ST-segment elevation myocardial infarction (STEMI), a severe form of heart attack. It aims to gather comprehensive clinical, biological, and imaging data to identify predictive factors for prognosis and understand the mechanisms leading to complications such as left ventricular remodeling and myocardial inflammation. Participants will undergo cardiac MRI and provide biological samples, including blood and urine, to facilitate this research. The goal is to improve the management and outcomes for patients suffering from this condition.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have been hospitalized for a myocardial infarction and can comply with study procedures.
Not a fit: Patients with contraindications to MRI or those who do not meet the inclusion criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better predictive tools and treatment strategies for patients who have suffered a myocardial infarction.
How similar studies have performed: Other studies have shown promise in using imaging and biological assessments to improve outcomes in myocardial infarction, but this specific approach is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient ≥18 years old, hospitalised in cardiology departments at the C.H.U. of Poitiers * Myocardial infarction type 1, 2 or 3 according to the 4th universal definition, with elevation of ST segment ≥0.2 milliVolt in two contiguous derivations of the ECG. * Patient able to comply with study procedures * Patient legally free and not subject to any custody, guardianship, tutelage or subordination measures * Informed consent signed by the patient/relative or trusted person after clear and complete information about the clinical investigation. Exclusion Criteria: * Subject with contraindication to MRI : pregnancy, ocular metallic foreign body (accidental or other chips), pace-maker incompatible with MRI, foreign ferromagnetic ocular or cerebral bodies, cochlear implants and in general all electronic medical material immovably implanted and incompatible with MRI; metallic heart valve of 1st generation, vascular clips formerly implanted on cranial aneurysm, severe renal insufficiency * Patient suffering from claustrophobia * Hypersensitivity to gadoteric acid, to meglumine or to a drug containing gadolinium * patients with insufficient venous access for contrast medium injection. * Participation in another interventional study with an investigational drug or device, which, in the judgment of the investigator, could interfere with the present study * Patients not benefiting from a Social Security scheme or not benefiting from it through a third party * Persons benefitting from enhanced protection, namely minors, pregnant women, persons deprived of their liberty by a judicial or administrative decision, patients staying in a health or social establishment, adults under legal protection
Where this trial is running
Poitiers
- C.H.U. of Poitiers — Poitiers, France (Recruiting)
Study contacts
- Study coordinator: Claire Bouleti, MD
- Email: claire.bouleti@chu-poitiers.fr
- Phone: +33 5 49 44 43 25
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.