Assessing heart function in patients with myotonic dystrophy type 1
Diastolic Function in Myotonic Dystrophy Type 1
This study looks at how common heart problems are in people with myotonic dystrophy type 1 to better understand their heart health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Sex | All |
| Sponsor | Centre d'Investigation Clinique et Technologique 805 Academic / other |
| Locations | 1 site (Garches) |
| Trial ID | NCT06029192 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients with myotonic dystrophy type 1 (DM1) to evaluate the prevalence and grading of left ventricular diastolic dysfunction (DD). The research aims to understand how common DD is among DM1 patients and its long-term prognosis. By utilizing Doppler echocardiography, the study will gather data on heart function in this specific patient population, which is at risk for various cardiovascular issues. The findings could provide insights into the relationship between DM1 and heart health.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with genetically confirmed myotonic dystrophy type 1 who have undergone Doppler echocardiography.
Not a fit: Patients with significant valvular disease or wall motion abnormalities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring and management of heart health in patients with myotonic dystrophy type 1.
How similar studies have performed: While there may be studies on diastolic dysfunction in other populations, this specific focus on myotonic dystrophy type 1 is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients with genetic proven myotonic dystrophy type 1 * who experienced a Doppler- Echocardiography including an assessment of the left ventricular diastolic function Exclusion Criteria: * wall motion basal abnormalities * significant valvular disease
Where this trial is running
Garches
- Hopital Raymond Poincare — Garches, France (Recruiting)
Study contacts
- Principal investigator: Abdallah FAYSSOIL, MD PhD — CHU Raymond Poincare
- Study coordinator: Abdallah FAYSSOIL, MD PhD
- Email: abdallah.fayssoil@aphp.fr
- Phone: +33147107778
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.