Assessing gastric cancer risk using endoscopic techniques
Different Endoscopic Gastric Cancer Risk Assessments for the Detection of Early Gastric Cancer
This study is testing if two specific tools can help doctors better spot early signs of gastric cancer in people aged 40 to 80 during endoscopic exams.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 3500 (estimated) |
| Ages | 40 Years to 80 Years |
| Sex | All |
| Sponsor | Shandong University Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT05458388 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of the Kimura-Takamoto classification and the EGGIM score in assessing the risk of gastric cancer during endoscopic examinations. By focusing on high-risk groups, the study aims to improve the detection rate of early gastric cancer, which is often missed due to its hidden lesions. Patients aged 40-80 undergoing gastroscopy will be included, and the study will analyze how these risk assessment tools can guide targeted examinations. The goal is to provide a clearer understanding of their diagnostic value in population screening for gastric cancer.
Who should consider this trial
Good fit: Ideal candidates are patients aged 40-80 who are undergoing gastroscopy and intend to have endoscopic submucosal dissection (ESD) treatment.
Not a fit: Patients with severe comorbidities, previous stomach surgeries, or those who refuse to consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection of gastric cancer, improving patient outcomes and survival rates.
How similar studies have performed: While the Kimura-Takamoto classification and EGGIM score have shown promise in previous studies, this approach to population screening is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 40-80 years undergoing gastroscopy * Patients intend to undergo ESD treatment Exclusion Criteria: * patients with severe cardiac, cerebral, pulmonary or renal dysfunction or psychiatric disorders who cannot participate in gastroscopy * Patients with previous surgical procedures on the stomach * patients with contraindications to biopsy * Patients who refuse to sign the informed consent form.
Where this trial is running
Jinan, Shandong
- Qilu Hospital, Shandong University — Jinan, Shandong, China (Recruiting)
Study contacts
- Study coordinator: Yan-qing Li
- Email: liyanqing@sdu.edu.cn
- Phone: +8653188369277
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.