Assessing frailty in patients undergoing left atrial appendage closure
Frailty in Patient Undergoing Percutaneous Left Atrial Appendage Closure The Frail-LAAC Study
This study is trying to see how frailty affects the health and quality of life of patients getting a specific heart procedure called left atrial appendage closure.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Institut universitaire de cardiologie et de pneumologie de Québec, University Laval Academic / other |
| Locations | 1 site (Québec, Quebec) |
| Trial ID | NCT05257954 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the prevalence and severity of frailty in patients who are undergoing transcatheter left atrial appendage closure (LAAC). It will investigate the relationship between frailty and both peri-procedural and long-term outcomes, as well as the impact on patients' quality of life. The study recognizes that while LAAC is a promising alternative to anticoagulation therapy, the high-risk nature of the patient population necessitates better selection criteria to improve outcomes. By understanding frailty in this context, the study seeks to enhance patient management and procedural success.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are undergoing transcatheter LAAC.
Not a fit: Patients who are unable to provide informed consent or have severe neuropsychiatric impairment may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved patient selection and outcomes for those undergoing LAAC.
How similar studies have performed: Other studies have highlighted the importance of patient selection in LAAC procedures, indicating that this approach is relevant and necessary.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Transcatheter LAAC with any approved device * Age ≥18 years old Exclusion Criteria: * Unable to provide informed consent * Severe neuropsychiatric impairment
Where this trial is running
Québec, Quebec
- Iucpq_ul — Québec, Quebec, Canada (Recruiting)
Study contacts
- Study coordinator: Josep Rodes-Cabau, MD, PhD
- Email: josep.rodes@criucpq.ulaval.ca
- Phone: 418-656-8711
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.