Assessing exercise capacity and fitness in children with congenital adrenal hyperplasia

A Comparison of Exercise Capacity, Muscle Functions, Physical Fitness, and Physical Activity Levels in Children With Congenital Adrenal Hyperplasia and Healthy Controls

Observational Hacettepe University · NCT06449456

This study is testing how congenital adrenal hyperplasia affects the exercise ability and fitness of children and teens compared to their healthy friends.

Quick facts

Study typeObservational
Enrollment40 (estimated)
Ages8 Years to 18 Years
SexAll
SponsorHacettepe University Academic / other
Locations1 site (Ankara, State)
Trial IDNCT06449456 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the exercise capacity, physical fitness, and activity levels of children and adolescents diagnosed with congenital adrenal hyperplasia (CAH) compared to healthy peers. It focuses on understanding how CAH affects respiratory and peripheral muscle strength, as well as overall physical performance. The study will involve participants aged 8 to 18 years, who will be assessed for various metabolic and cardiovascular parameters that may influence their quality of life. The findings could provide insights into the specific challenges faced by this population in terms of physical activity.

Who should consider this trial

Good fit: Ideal candidates for this study are children and adolescents aged 8-18 years who have been diagnosed with congenital adrenal hyperplasia.

Not a fit: Patients with systemic diseases that may affect measurement parameters or those unable to cooperate may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for enhancing physical fitness and quality of life in children with CAH.

How similar studies have performed: While there have been studies on exercise capacity in other populations, this specific focus on children with CAH is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria for CAH Group:

* Diagnosed with Congenital Adrenal Hyperplasia
* Aged between 8-18 years
* Providing voluntary consent from both themselves and their parents
* Able to cooperate

Exclusion Criteria for CAH Groups:

- Having any systemic disease that may affect the measurement parameters

Inclusion Criteria for Healthy Group:

* Not having any chronic diseases
* Aged between 8-18 years
* Willing to participate in the study
* Able to cooperate

Exclusion Criteria for Healthy Group:

* Not willing to participate in the study
* Presence of cooperation and communication problems

Where this trial is running

Ankara, State

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Congenital Adrenal HyperplasiaExercise CapacityPhysical ActivityQuality of LifeCongenital Adrenal HyperplesiaPhysical FitnessHeart Rate Variability - HRV
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.