Clinical trial Recruiting at 2 sites Observational Ages 50 and up

Assessing driving performance in older adults using medical marijuana

Official title: An Open Road Driving Performance Task to Examine Long-term Medical Marijuana Use and Prescription Opioid Positivity in Adults 50 and Older

Run by Florida State University · NCT06995937 · Data updated 2026-11-12

This study is testing how using medical marijuana affects driving skills in adults aged 50 and older who have chronic pain, comparing those who use it with those who haven't used it in a long time.

Quick facts

Study typeObservational
Ages50 Years and up
SexAll
Enrollment250 (estimated)
SponsorFlorida State University
Academic / other
Locations2 sites (Gainesville, Florida and 1 other locations)
StatusRecruiting
StartedMay 19, 2025
Main results expectedJanuary 30, 2029
Study endsJanuary 30, 2029
Registry record updatedAugust 20, 2026
Trial IDNCT06995937 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 50 and older with chronic or severe non-malignant pain who have an active medical marijuana card and a valid Florida driver's license.

Probably not a fit

Patients with active psychosis or those who have lost their driving privileges will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines the impact of medical marijuana use on driving performance among adults aged 50 and older who experience chronic or severe non-malignant pain. It aims to systematically assess how long-term medical marijuana use and the combined effect of prescription opioids influence driving behavior in this demographic. The study will include participants with an active medical marijuana card and those who have not used marijuana in the past decade, allowing for a comparative analysis of driving performance. The research is conducted in Florida, focusing on the self-regulation of medication use and driving among older adults.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the safety of driving for older adults using medical marijuana, potentially influencing guidelines and policies.

How similar studies have gone: While there is limited research on this specific demographic and context, studies on medical marijuana and driving have shown mixed results, indicating a need for further investigation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 50 and older who endorse chronic or severe non-malignant pain
* Resident of Florida with an active and valid Florida Drivers License
* Can communicate in English
* Willing and able to complete study procedures
* Have active medical marijuana card for \>12 months issued by the state of Florida (MMG group) OR are race-sex match who has not used marijuana in the past 10 years with no history of daily use (NMG group)

Exclusion Criteria:

* Have active psychosis
* Have lost or revoked driving privileges
* Score of below the cut 24 (out of 30) on the Montreal Cognitive Assessment (MoCA)
* Are a control participant who urine test positive for marijuana use and/or reports any marijuana use in past 10 years

Where it's running

  • University of Florida
    Gainesville, Florida, United States
    Recruiting
  • Florida State University, Center for Translational Behavioral Science
    Tallahassee, Florida, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.