Assessing dental and periodontal health in Sjögren's syndrome patients
Prevalence and Characteristics of Dental and Periodontal Lesions in Patients With Sjögren's Syndrome. Establishment of a Biological Saliva Collection.
This study looks at how common dental wear and gum problems are in people with Sjögren's syndrome to see how these issues relate to inflammation and saliva.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Ivry-sur-Seine, Île-de-France Region) |
| Trial ID | NCT04848870 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the prevalence of dental wear and gingival recession in patients diagnosed with Sjögren's syndrome. By utilizing the Basic Erosive Wear Examination (BEWE) and Basic Erosive Wear Abrasion (BEWA) scores, researchers will analyze the extent of erosions and attrition, as well as the percentage of periodontal sites with significant recession. Additionally, the study will explore correlations between dental and gingival wear, inflammation, and various salivary parameters. Salivary samples will be collected for future research on associated risks of dental and periodontal issues.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old who have been diagnosed with Sjögren's syndrome and can communicate effectively in French.
Not a fit: Patients who do not have Sjögren's syndrome or those who oppose participation in the study will not benefit.
Why it matters
Potential benefit: If successful, this study could enhance understanding of oral health challenges faced by Sjögren's syndrome patients, leading to improved dental care strategies.
How similar studies have performed: While there is limited literature specifically addressing dental wear in Sjögren's syndrome, similar studies on oral health in autoimmune conditions have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient with Sjögren Syndrome * Patient \> 18 years old * Patient affiliated to a social security system, beneficiary or beneficiary of a right other than AME * Patient who speaks and understands French well enough to be able to read and understand the study information note. * Patient who does not object to his participation in the study Exclusion Criteria: \- Patient having expressed his opposition to participate in the research
Where this trial is running
Ivry-sur-Seine, Île-de-France Region
- Service de Médecine bucco-dentaire — Ivry-sur-Seine, Île-de-France Region, France (Recruiting)
Study contacts
- Principal investigator: Marjolaine GOSSET, PUPH — Assistance Publique - Hôpitaux de Paris
- Study coordinator: Marjolaine GOSSET, PU-PH
- Email: marjolaine.gosset@aphp.fr
- Phone: +33 6 19 39 39 01
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.