Assessing COVID-19 Risks and Hospitalization Outcomes

COVID-19 Risk Assessment Hospitalization Outcomes Epidemiology Efficacy

Observational Aventyn, Inc. · NCT04678193

This study is testing a new way to track COVID-19 symptoms and risks using a mobile app, while also seeing if a specific drug can help reduce hospital visits for people who test positive for the virus.

Quick facts

Study typeObservational
Enrollment27000 (estimated)
Ages18 Years and up
SexAll
SponsorAventyn, Inc. Industry-sponsored
Locations3 sites (Phoenix, Arizona and 2 other locations)
Trial IDNCT04678193 on ClinicalTrials.gov

What this trial studies

This study aims to create a real-time epidemiology registry to evaluate COVID-19 risk assessment scores by recording symptoms, biomarkers, chronic illnesses, and mental health using digital technology. Researchers will monitor both PCR positive and negative subjects to understand variations in COVID-19 presentation and identify predictors for hospitalization and post-COVID complications. The study will also compare the efficacy of the ECL-19 drug against a placebo in reducing hospital admissions among COVID-19 positive patients. Participants can self-report their health status through a mobile app, enabling continuous monitoring and assessment.

Who should consider this trial

Good fit: Ideal candidates include individuals who are COVID-19 PCR positive, negative, or pending, as well as those with a high-risk score for COVID-19.

Not a fit: Patients who are unwilling to participate or considered unreliable for follow-up may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of COVID-19 risks and improve strategies to prevent hospitalizations.

How similar studies have performed: Other studies have shown promise in using digital health technologies for monitoring COVID-19, but this approach is innovative in its comprehensive risk assessment methodology.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* COVID-19 PCR positive
* COVID-19 PCR negative
* COVID-19 PCR pending
* COVID-19 high risk score

Exclusion Criteria:

* Subjects unwilling to participate in the study before, during or after consent
* Patients considered unreliable by the investigator concerning the requirements for follow-up visits.

Where this trial is running

Phoenix, Arizona and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Covid19
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.