Assessing corneal properties in patients with pseudoexfoliation syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the impact of pseudoexfoliation syndrome on corneal biomechanics, optical clarity, and anterior segment structural features. Patients aged 60-80 with pseudoexfoliation syndrome will undergo a series of examinations using advanced imaging technologies, including Pentacam-AXL and Corvis ST, to assess corneal optical properties and biomechanical parameters. The results will be compared to a control group of age-matched individuals without the syndrome to better understand the effects of this condition on the eye.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age 60-80 years.
* unilateral or bilateral pseudophakia (cataract surgery undergone at Papageorgiou General Hospital, Thessaloniki, Greece).
* open anterior chamber angle (grade \> 2, van Herick method).

Exclusion Criteria:

* History of intraocular surgery other than uncomplicated cataract surgery (phakoemulsification).
* Cataract surgery within the last 3 months.
* History of ocular trauma.
* Use of contact lenses.
* Corneal pathology.
* Use of anti-VEGF medications.
* History of uveitis or active uveitis.
* Hypertension (IOP \> 21 mmHg) or glaucoma.
* Myopia or hyperopia greater than 3 diopters.
* Astigmatism greater than 1.5 diopters.
* Posterior capsular opacification grade 2, 3, or 4 based on the EPCO grading scale.
* Tear break-up time \<10 sec

Where it's running

• 2nd Department of Ophthalmology, Papageorgiou General Hospital
  Thessaloniki, Greece Recruiting

Study contacts

• Study coordinator: Paraskevi Petridou, MD, MSc
• Email: evina_petridou@hotmail.com
• Phone: 00306985565799

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Comparing two methods for lens implantation in cataract surgery for patients with pseudoexfoliation syndrome

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.