Assessing Conscious Awareness in Epilepsy Using EEG
Objective EEG Bed Side Assessment of Impaired Conscious Awareness in Epilepsy
This study is testing if EEG readings can help us understand conscious awareness in people with absence epilepsy and see how it differs from healthy individuals.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Schleswig-Holstein Academic / other |
| Locations | 1 site (Kiel) |
| Trial ID | NCT04799795 on ClinicalTrials.gov |
What this trial studies
This project compares EEG recordings from healthy participants and those diagnosed with absence epilepsy to identify differences in EEG microstate analysis and neuropsychological parameters related to cognitive impairment. The goal is to derive an EEG-based measure of conscious awareness that can be applied in the care of epilepsy patients. The study aims to demonstrate that cognitive impairment can occur during interictal states, challenging the traditional understanding of epilepsy phases. By establishing objective markers of conscious awareness, the research could influence clinical practices and treatment evaluations.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with a diagnosis of absence epilepsy or healthy age-matched controls.
Not a fit: Patients with central nervous system disorders other than epilepsy, substance abuse issues, or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved assessment and management of cognitive impairment in epilepsy patients.
How similar studies have performed: While the approach of using EEG to assess cognitive impairment in epilepsy is innovative, similar studies have shown promise in understanding interictal states, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age minimum 18 years * diagnosis of (absence) epilepsy // healthy age-matched controls * being of good health (besides epilepsy in the case group) Exclusion Criteria: * central nervous system disorders (besides epilepsy in the case group) * substance abuse * pregnancy
Where this trial is running
Kiel
- Department of Neurology — Kiel, Germany (Recruiting)
Study contacts
- Principal investigator: Inken Toedt, Dr. phil. Dipl.-Psych. — University Hospital Schleswig-Holstein, Kiel
- Study coordinator: Inken Toedt, Dr. phil. Dipl.-Psych.
- Email: inken.toedt@uksh.de
- Phone: 0049 431 500 23985
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.