Assessing cognitive symptoms in severe sleep apnea patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational pilot study aims to evaluate 'Brain Fog'—cognitive symptoms affecting memory, attention, and concentration—in patients with severe Obstructive Sleep Apnea (OSA). It compares two groups: those who have been on CPAP treatment for at least 3 months and those who have not yet started treatment. Participants will complete a 30-minute questionnaire at the Sleep Center Clinic, which includes assessments of daytime sleepiness, sleep quality, and psychophysical fatigue. The study will involve 80 outpatients, evenly divided by age and gender, over a duration of approximately 12 months.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with severe OSA treated with CPAP for at least 3 months.
* Patients with severe OSA in new access and therefore not yet subjected to CPAP treatment.
* Patients with severe OSA who are able to understand the Italian language.

Exclusion Criteria:

* Patients who do not have a certified diagnosis of severe OSA.
* Patients with mild or moderate OSA.
* Patients with OSA who are unable to understand the Italian language.
* Patients with OSA who have neurological and/or oncological comorbidities, as verified by medical records.
* Patients with documented cognitive deficits, as verified by medical records.
* Patients with certified diagnoses of psychiatric disorders and/or substance use disorders (SUD), as verified by medical records.

Where it's running

• IRCCS Fondazione Don Gnocchi
  Milan, Mi, Italy Recruiting

Study contacts

• Study coordinator: Eleonora Volpato, PhD
• Email: eleonora.volpato@unicatt.it
• Phone: 3293782692

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.