Assessing cerebrospinal fluid flow disorders using MRI techniques
Assessment of Cerebrospinal Fluid Flow Related Disorders Using a Phase-contrast Magnetic Resonance Imaging Technique.
This study is testing a special MRI technique to see if it can help doctors better understand and diagnose problems with cerebrospinal fluid flow in patients showing related symptoms.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 87 (estimated) |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Assiut) |
| Trial ID | NCT03656016 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate cerebrospinal fluid flow disorders through the use of phase-contrast magnetic resonance imaging (MRI). The study will involve patients of various ages who exhibit clinical signs suggestive of cerebrospinal fluid flow issues, as identified by conventional MRI. The phase-contrast MRI technique is non-invasive and allows for both qualitative and quantitative assessment of cerebrospinal fluid dynamics, helping to identify conditions such as hydrocephalus and Chiari malformation. By providing detailed imaging, the study seeks to enhance diagnostic accuracy and inform treatment decisions.
Who should consider this trial
Good fit: Ideal candidates include patients of all ages with clinical findings indicative of cerebrospinal fluid flow disorders.
Not a fit: Patients with contraindications for MRI, such as implanted devices or those with ventriculomegaly due to brain lesions, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and management of cerebrospinal fluid flow disorders.
How similar studies have performed: Other studies utilizing advanced MRI techniques have shown promise in diagnosing cerebrospinal fluid disorders, indicating that this approach is supported by prior research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with different age groups and both sex with clinical and routine conventional magnetic resonance imaging findings suggestive of cerebrospinal fluid flow disorders. Exclusion Criteria: 1. Patients with contraindications for MRI, e.g. an implanted magnetic device, pacemakers or claustrophobia. 2. Patients with VP shunts 3. Patients with ventriculomegally due to brain SOLs.
Where this trial is running
Assiut
- Faculty of medicine — Assiut, Egypt (Recruiting)
Study contacts
- Principal investigator: Shimaa Bakr, MSc — Assiut University
- Study coordinator: Mostafa Hussein
- Email: thabet.mostafa@yahoo.com
- Phone: 01122999878
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.